134872

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 257606..257790 Replicon chromosome
Accession NZ_CP042107
Organism Staphylococcus aureus strain B8-13D

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag FP484_RS01395 Protein ID WP_000482652.1
Coordinates 257683..257790 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 257606..257666 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FP484_RS01380 253061..253228 - 168 Protein_271 hypothetical protein -
FP484_RS01385 253459..255192 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
FP484_RS01390 255217..256980 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 257606..257666 + 61 - - Antitoxin
FP484_RS01395 257683..257790 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
FP484_RS01400 257924..258310 - 387 WP_000779360.1 flippase GtxA -
FP484_RS01405 258578..259720 + 1143 WP_001176863.1 glycerate kinase -
FP484_RS01410 259780..260439 + 660 WP_000831298.1 membrane protein -
FP484_RS01415 260621..261832 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
FP484_RS01420 261955..262428 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T134872 WP_000482652.1 NZ_CP042107:c257790-257683 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T134872 NZ_CP042107:c257790-257683 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT134872 NZ_CP042107:257606-257666 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References