Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 316125..316388 Replicon chromosome
Accession NZ_CP042046
Organism Staphylococcus aureus strain B2-7A

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FP477_RS01865 Protein ID WP_001802298.1
Coordinates 316284..316388 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 316125..316289 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FP477_RS01845 312365..313030 - 666 WP_001024095.1 SDR family oxidoreductase -
FP477_RS01850 313182..313502 + 321 WP_145389792.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FP477_RS01855 313504..314484 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
FP477_RS01860 314750..315841 + 1092 WP_000495683.1 hypothetical protein -
- 316125..316289 + 165 - - Antitoxin
FP477_RS01865 316284..316388 - 105 WP_001802298.1 hypothetical protein Toxin
FP477_RS01870 316549..317032 - 484 Protein_323 recombinase family protein -
FP477_RS01875 317075..318211 - 1137 WP_000115564.1 SAP domain-containing protein -
FP477_RS01880 318500..318592 + 93 WP_001790138.1 hypothetical protein -
FP477_RS01885 319297..320154 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
FP477_RS01890 320222..321004 - 783 WP_000908177.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T134865 WP_001802298.1 NZ_CP042046:c316388-316284 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T134865 NZ_CP042046:c316388-316284 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT134865 NZ_CP042046:316125-316289 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References