134858

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2730690..2730874 Replicon chromosome
Accession NZ_CP042043
Organism Staphylococcus aureus strain B2-15A

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag FP478_RS13865 Protein ID WP_000482652.1
Coordinates 2730767..2730874 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2730690..2730750 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FP478_RS13850 2726145..2726312 - 168 Protein_2630 hypothetical protein -
FP478_RS13855 2726543..2728276 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
FP478_RS13860 2728301..2730064 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 2730690..2730750 + 61 - - Antitoxin
FP478_RS13865 2730767..2730874 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
FP478_RS13870 2731008..2731394 - 387 WP_000779360.1 flippase GtxA -
FP478_RS13875 2731662..2732804 + 1143 WP_001176863.1 glycerate kinase -
FP478_RS13880 2732864..2733523 + 660 WP_000831298.1 membrane protein -
FP478_RS13885 2733705..2734916 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
FP478_RS13890 2735039..2735512 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T134858 WP_000482652.1 NZ_CP042043:c2730874-2730767 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T134858 NZ_CP042043:c2730874-2730767 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT134858 NZ_CP042043:2730690-2730750 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References