Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 817444..817723 Replicon chromosome
Accession NZ_CP042003
Organism Staphylococcus aureus strain B3-14B

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FP480_RS03940 Protein ID WP_001802298.1
Coordinates 817444..817548 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 817544..817723 (-)

Genomic Context


FP480_RS03905FP480_RS03910FP480_RS03915FP480_RS03940FP480_RS03960FP480_RS03920FP480_RS03925FP480_RS14855--FP480_RS03945FP480_RS03950FP480_RS03955
Location: 813343..813951 (609 bp)
Type: Others
Protein ID: WP_000101714.1
Location: 814241..815023 (783 bp)
Type: Others
Protein ID: WP_000908191.1
Location: 815091..815948 (858 bp)
Type: Others
Protein ID: WP_000370942.1
Location: 817444..817548 (105 bp)
Type: Toxin
Protein ID: WP_001802298.1
Location: 820857..821522 (666 bp)
Type: Others
Protein ID: WP_001024099.1
Location: 816078..816170 (93 bp)
Type: Others
Protein ID: WP_000220902.1
Location: 816606..816764 (159 bp)
Type: Others
Protein ID: WP_001792784.1
Location: 816757..816927 (171 bp)
Type: Others
Protein ID: WP_001807897.1
Location: 817544..817723 (180 bp)
Type: Antitoxin
Protein ID: -
Location: 818046..819137 (1092 bp)
Type: Others
Protein ID: WP_000495673.1
Location: 819403..820383 (981 bp)
Type: Others
Protein ID: WP_000019735.1
Location: 820385..820705 (321 bp)
Type: Others
Protein ID: WP_000003759.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FP480_RS03905813343..813951+609WP_000101714.1TIR domain-containing protein-
FP480_RS03910814241..815023+783WP_000908191.1ABC transporter ATP-binding protein-
FP480_RS03915815091..815948+858WP_000370942.1Cof-type HAD-IIB family hydrolase-
FP480_RS03920816078..816170-93WP_000220902.1hypothetical protein-
FP480_RS03925816606..816764-159WP_001792784.1hypothetical protein-
FP480_RS14855816757..816927-171WP_001807897.1hypothetical protein-
FP480_RS03940817444..817548+105WP_001802298.1hypothetical proteinToxin
-817544..817723-180--Antitoxin
FP480_RS03945818046..819137-1092WP_000495673.1hypothetical protein-
FP480_RS03950819403..820383-981WP_000019735.1CDF family zinc efflux transporter CzrB-
FP480_RS03955820385..820705-321WP_000003759.1Zn(II)-responsive metalloregulatory transcriptional repressor CzrA-
FP480_RS03960820857..821522+666WP_001024099.1SDR family oxidoreductase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T134831 WP_001802298.1 NZ_CP042003:817444-817548 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T134831 NZ_CP042003:817444-817548 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 180 bp

>AT134831 NZ_CP042003:c817723-817544 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A2I7Y9L9


Antitoxin

Download structure file

References