Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 817444..817707 Replicon chromosome
Accession NZ_CP042003
Organism Staphylococcus aureus strain B3-14B

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FP480_RS03940 Protein ID WP_001802298.1
Coordinates 817444..817548 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 817543..817707 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FP480_RS03905 813343..813951 + 609 WP_000101714.1 TIR domain-containing protein -
FP480_RS03910 814241..815023 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
FP480_RS03915 815091..815948 + 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
FP480_RS03920 816078..816170 - 93 WP_000220902.1 hypothetical protein -
FP480_RS03925 816606..816764 - 159 WP_001792784.1 hypothetical protein -
FP480_RS14855 816757..816927 - 171 WP_001807897.1 hypothetical protein -
FP480_RS03940 817444..817548 + 105 WP_001802298.1 hypothetical protein Toxin
- 817543..817707 - 165 - - Antitoxin
FP480_RS03945 818046..819137 - 1092 WP_000495673.1 hypothetical protein -
FP480_RS03950 819403..820383 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
FP480_RS03955 820385..820705 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FP480_RS03960 820857..821522 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T134830 WP_001802298.1 NZ_CP042003:817444-817548 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T134830 NZ_CP042003:817444-817548 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT134830 NZ_CP042003:c817707-817543 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References