Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 3418587..3419095 Replicon chromosome
Accession NZ_CP041765
Organism Tomitella sp. HY188

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag FO059_RS15575 Protein ID WP_143909885.1
Coordinates 3418587..3418847 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FO059_RS15580 Protein ID WP_143909886.1
Coordinates 3418844..3419095 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FO059_RS15560 3415154..3416023 + 870 WP_143909882.1 aldo/keto reductase -
FO059_RS15565 3416075..3417364 + 1290 WP_143909883.1 phosphatase PAP2 family protein -
FO059_RS15570 3417443..3418525 + 1083 WP_143909884.1 phosphotransferase family protein -
FO059_RS15575 3418587..3418847 - 261 WP_143909885.1 Txe/YoeB family addiction module toxin Toxin
FO059_RS15580 3418844..3419095 - 252 WP_143909886.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FO059_RS15585 3419303..3420661 - 1359 WP_143909887.1 MFS transporter -
FO059_RS15590 3420700..3420954 + 255 WP_143909888.1 hypothetical protein -
FO059_RS15595 3420976..3422010 - 1035 WP_143909889.1 glutathione S-transferase C-terminal domain-containing protein -
FO059_RS15600 3422118..3422714 + 597 WP_143909890.1 methyltransferase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10495.87 Da        Isoelectric Point: 8.8895

>T129202 WP_143909885.1 NZ_CP041765:c3418847-3418587 [Tomitella sp. HY188]
MRLVWDESAWDDYLWWQAQDRKTLKRINALIRDIQWNGNEGIGKPEQLRHGFQGYWSRRITLEHRLVYKMTGDEIRVAAC
RYHYGE

Download         Length: 261 bp

>T129202 NZ_CP041765:c3418847-3418587 [Tomitella sp. HY188]
ATGAGGCTGGTCTGGGACGAGTCGGCGTGGGATGACTACCTGTGGTGGCAGGCGCAGGACCGCAAGACGCTCAAGCGCAT
CAATGCGCTGATCCGCGATATCCAGTGGAACGGCAATGAGGGCATCGGGAAGCCCGAGCAGCTCAGACACGGATTCCAGG
GTTACTGGTCGCGGCGGATCACCCTGGAGCACCGGTTGGTGTACAAGATGACCGGCGACGAGATCCGCGTCGCCGCGTGC
CGATACCACTACGGGGAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9402.47 Da        Isoelectric Point: 4.2906

>AT129202 WP_143909886.1 NZ_CP041765:c3419095-3418844 [Tomitella sp. HY188]
VRTISYSESRARYAETLDSVIDDREEVIVTRAGRDPVVMVALDEYESLKETAYLLKSPENARRLLASIERLESGEGVERD
LAE

Download         Length: 252 bp

>AT129202 NZ_CP041765:c3419095-3418844 [Tomitella sp. HY188]
GTGCGGACGATCTCCTATTCGGAATCCCGGGCGCGGTACGCGGAGACGCTTGACAGCGTCATCGACGATCGCGAGGAGGT
CATCGTCACGCGTGCGGGCCGCGACCCGGTGGTGATGGTGGCTCTCGACGAGTACGAGTCCCTCAAGGAGACCGCGTACC
TGCTCAAGAGTCCAGAAAATGCGCGTCGCCTCCTCGCCTCCATCGAGCGGCTCGAATCGGGAGAAGGGGTCGAGCGGGAT
CTCGCCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References