Detailed information of TA system TA129181

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrG-as-bsrH/-
• Location: 2273191..2273481
• Replicon: chromosome
• Accession: NZ_CP041757
• Organism: Bacillus sp. KBS0812

Toxin (Protein)

• Gene name: bsrG
• Uniprot ID: L8EAY0
• Locus tag: FFE90_RS11825
• Protein ID: WP_009967548.1
• Coordinates: 2273191..2273307 (+)
• Length: 39 a.a.

Antitoxin (RNA)

Gene name	as-bsrH
Locus tag	-
Coordinates	2273302..2273481 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FFE90_RS11790	2269118..2269288	-	171	WP_009967544.1	bacteriocin sublancin-168	-
FFE90_RS11795	2269585..2269902	-	318	WP_009967545.1	sublancin immunity protein SunI	-
FFE90_RS11800	2270004..2271254	-	1251	WP_004398504.1	UV-damage repair protein uvrX	-
FFE90_RS11805	2271247..2271579	-	333	WP_004398710.1	YolD-like family protein	-
FFE90_RS11810	2271753..2272088	+	336	WP_004399073.1	hypothetical protein	-
FFE90_RS11815	2272131..2272487	-	357	WP_004398595.1	hypothetical protein	-
FFE90_RS11820	2272493..2272960	-	468	WP_003246138.1	YolA family protein	-
FFE90_RS11825	2273191..2273307	+	117	WP_009967548.1	type I toxin-antitoxin system toxin BsrG	Toxin
-	2273302..2273481	-	180	NuclAT_1	-	Antitoxin
-	2273302..2273481	-	180	NuclAT_1	-	Antitoxin
-	2273302..2273481	-	180	NuclAT_1	-	Antitoxin
-	2273302..2273481	-	180	NuclAT_1	-	Antitoxin
FFE90_RS11830	2273586..2274119	-	534	WP_004399156.1	GNAT family N-acetyltransferase	-
FFE90_RS11835	2274155..2274733	-	579	WP_004399123.1	SMI1/KNR4 family protein	-
FFE90_RS11840	2274797..2275294	-	498	WP_003246188.1	SMI1/KNR4 family protein	-
FFE90_RS11845	2275303..2277018	-	1716	WP_004398855.1	ribonuclease YeeF family protein	-
FFE90_RS11850	2277118..2277675	-	558	WP_003246042.1	SMI1/KNR4 family protein	-
FFE90_RS11855	2277759..2277944	+	186	WP_003245951.1	transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2151223..2286005	134782

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-38)

Sequences

Toxin

Protein

• Length: 39 a.a.
• Molecular weight: 4336.39 Da
• Isoelectric Point: 10.1022

>T129181 WP_009967548.1 NZ_CP041757:2273191-2273307 [Bacillus sp. KBS0812]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Nucleotide

• Length: 117 bp

>T129181 NZ_CP041757:2273191-2273307 [Bacillus sp. KBS0812]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin

Nucleotide

• Length: 180 bp

>AT129181 NZ_CP041757:c2273481-2273302 [Bacillus sp. KBS0812]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Structures

Toxin

• AlphaFold DB: A0A7Z7EVU9

Antitoxin