Detailed information of TA system TA129171

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 2219111..2219440
• Replicon: chromosome
• Accession: NZ_CP041757
• Organism: Bacillus sp. KBS0812

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: C0H439
• Locus tag: FFE90_RS11525
• Protein ID: WP_010886546.1
• Coordinates: 2219111..2219362 (-)
• Length: 84 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2219340..2219440 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FFE90_RS11500	2214569..2214796	-	228	WP_004399298.1	helix-turn-helix transcriptional regulator	-
FFE90_RS11505	2215057..2216373	-	1317	WP_004399369.1	hypothetical protein	-
FFE90_RS11510	2216730..2217236	-	507	WP_004399486.1	hypothetical protein	-
FFE90_RS11515	2217564..2218796	-	1233	WP_004399445.1	hypothetical protein	-
FFE90_RS11520	2218878..2219066	-	189	WP_004399547.1	hypothetical protein	-
FFE90_RS11525	2219111..2219362	-	252	WP_010886546.1	hypothetical protein	Toxin
-	2219340..2219440	+	101	-	-	Antitoxin
FFE90_RS11530	2219381..2219557	-	177	WP_009967515.1	hypothetical protein	-
-	2219498..2219598	+	101	NuclAT_2	-	-
-	2219498..2219598	+	101	NuclAT_2	-	-
-	2219498..2219598	+	101	NuclAT_2	-	-
-	2219498..2219598	+	101	NuclAT_2	-	-
FFE90_RS11535	2219932..2220543	-	612	WP_009967516.1	lipoprotein	-
FFE90_RS11540	2220658..2220984	-	327	WP_009967517.1	helix-turn-helix domain-containing protein	-
FFE90_RS11545	2221937..2222131	+	195	WP_004399291.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2151223..2286005	134782

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (8-95)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9956.96 Da
• Isoelectric Point: 9.7930

>T129171 WP_010886546.1 NZ_CP041757:c2219362-2219111 [Bacillus sp. KBS0812]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Nucleotide

• Length: 252 bp

>T129171 NZ_CP041757:c2219362-2219111 [Bacillus sp. KBS0812]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGGCGCTAA
TCAACACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTGTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin

Nucleotide

• Length: 101 bp

>AT129171 NZ_CP041757:2219340-2219440 [Bacillus sp. KBS0812]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Toxin

• AlphaFold DB: C0H439

Antitoxin