Detailed information of TA system TA129168

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2069410..2069725
• Replicon: chromosome
• Accession: NZ_CP041757
• Organism: Bacillus sp. KBS0812

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: FFE90_RS10440
• Protein ID: WP_120322743.1
• Coordinates: 2069410..2069571 (+)
• Length: 54 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2069552..2069725 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FFE90_RS10425	2064638..2064973	+	336	WP_009967409.1	hypothetical protein	-
FFE90_RS10430	2065020..2068625	-	3606	WP_004399367.1	membrane protein	-
FFE90_RS10435	2068858..2069190	-	333	WP_026009814.1	hypothetical protein	-
FFE90_RS10440	2069410..2069571	+	162	WP_120322743.1	putative holin-like toxin	Toxin
-	2069552..2069725	-	174	-	-	Antitoxin
FFE90_RS10445	2069840..2070682	-	843	WP_003231327.1	hypothetical protein	-
FFE90_RS10450	2070882..2071340	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
FFE90_RS10455	2071350..2073152	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
FFE90_RS10460	2073254..2073811	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2055464..2080690	25226

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (24-47)

Sequences

Toxin

Protein

• Length: 54 a.a.
• Molecular weight: 5780.74 Da
• Isoelectric Point: 4.6641

>T129168 WP_120322743.1 NZ_CP041757:2069410-2069571 [Bacillus sp. KBS0812]
ISCTVSFAHSRESCSSPNERGDAMSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 162 bp

>T129168 NZ_CP041757:2069410-2069571 [Bacillus sp. KBS0812]
ATTTCCTGTACAGTAAGTTTTGCTCACTCGAGGGAGTCTTGCTCATCCCCTAATGAAAGGGGTGATGCTATGTCAACATT
CCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAATAGACCTCCCTT
GA

Antitoxin

Nucleotide

• Length: 174 bp

>AT129168 NZ_CP041757:c2069725-2069552 [Bacillus sp. KBS0812]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin