Detailed information of TA system TA129111

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 46741..46955
• Replicon: plasmid p1
• Accession: NZ_CP041739
• Organism: Enterococcus faecalis EnGen0107 strain B594

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: SAW_RS16890
• Protein ID: WP_107164701.1
• Coordinates: 46741..46851 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	46891..46955 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAW_RS16850	42661..43281	+	621	WP_021732893.1	recombinase family protein	-
SAW_RS16855	43298..43585	+	288	WP_010708491.1	hypothetical protein	-
SAW_RS16860	43579..43803	+	225	WP_010714310.1	hypothetical protein	-
SAW_RS16865	43864..44073	+	210	WP_002393768.1	hypothetical protein	-
SAW_RS16870	44085..44387	+	303	WP_002393766.1	hypothetical protein	-
SAW_RS16875	44815..46143	+	1329	WP_010714311.1	Y-family DNA polymerase	-
SAW_RS16880	46140..46490	+	351	WP_002365943.1	hypothetical protein	-
SAW_RS16890	46741..46851	+	111	WP_107164701.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	46891..46955	-	65	-	-	Antitoxin
-	46891..46993	-	103	NuclAT_0	-	-
-	46891..46993	-	103	NuclAT_0	-	-
-	46891..46993	-	103	NuclAT_0	-	-
-	46891..46993	-	103	NuclAT_0	-	-
SAW_RS16895	47180..48358	-	1179	WP_000997695.1	IS256-like element ISEf1 family transposase	-
SAW_RS16900	48536..48997	+	462	WP_002365946.1	hypothetical protein	-
SAW_RS17455	49168..49458	+	291	WP_002365947.1	hypothetical protein	-
SAW_RS16910	49562..49933	-	372	WP_000049959.1	replication-associated protein RepC	-
SAW_RS16915	49926..50771	-	846	WP_000239313.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	asa1	1..70182	70182
	-	flank	IS/Tn	-	-	47180..48358	1178

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4090.89 Da
• Isoelectric Point: 4.1672

>T129111 WP_107164701.1 NZ_CP041739:46741-46851 [Enterococcus faecalis EnGen0107]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDSRK

Nucleotide

• Length: 111 bp

>T129111 NZ_CP041739:46741-46851 [Enterococcus faecalis EnGen0107]
GTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCAATCTTTGTAGGATTGGTTCTGGAAATGATTTCTCGTGT
GTTGGACGAGGAAGACGATAGCCGAAAGTAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT129111 NZ_CP041739:c46955-46891 [Enterococcus faecalis EnGen0107]
AACGACATTAAATCGTACAGATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin