Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 3052657..3053055 Replicon chromosome
Accession NZ_CP041738
Organism Enterococcus faecalis EnGen0107 strain B594

Toxin (Protein)


Gene name txpA Uniprot ID A0A4U3MBY2
Locus tag SAW_RS16095 Protein ID WP_002372618.1
Coordinates 3052858..3053055 (+) Length 66 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 3052657..3052811 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAW_RS16070 3048335..3048967 - 633 WP_002358972.1 RloB family protein -
SAW_RS16075 3048976..3050271 - 1296 WP_002379013.1 AAA family ATPase -
SAW_RS16090 3050733..3052349 + 1617 WP_002379014.1 phosphatase PAP2/LCP family protein -
- 3052657..3052811 - 155 - - Antitoxin
SAW_RS16095 3052858..3053055 + 198 WP_002372618.1 putative holin-like toxin Toxin
SAW_RS16100 3053245..3057003 - 3759 WP_010706868.1 WxL domain-containing protein -
SAW_RS16105 3057599..3057742 + 144 WP_002387585.1 putative holin-like toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(32-65)


Sequences

Toxin        


Download         Length: 66 a.a.        Molecular weight: 7516.13 Da        Isoelectric Point: 10.5649

>T129100 WP_002372618.1 NZ_CP041738:3052858-3053055 [Enterococcus faecalis EnGen0107]
MCREVMAVAIQSEREVMRMHVFPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 198 bp

>T129100 NZ_CP041738:3052858-3053055 [Enterococcus faecalis EnGen0107]
ATGTGTAGAGAAGTTATGGCGGTGGCTATCCAATCTGAAAGAGAGGTGATGCGTATGCACGTATTTCCGAAATTCACAGA
AAGGAGAGGCCTTTTGTCAGCATATGAAACAATTCAGACAATTCTTGGGTTTGGTATGTTTACCATTGCTTTGATTGCGC
TGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA

Antitoxin


Download         Length: 155 bp

>AT129100 NZ_CP041738:c3052811-3052657 [Enterococcus faecalis EnGen0107]
TTTTTAGGTAAGTGTGCTATAATAGCAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCGGTTTAAGA
CGGTGACCTTTTGGATTATTTAAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCTTCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4U3MBY2

Antitoxin

Download structure file

References