Detailed information of TA system TA129014

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrG-as-bsrG/-
• Location: 2101655..2101905
• Replicon: chromosome
• Accession: NZ_CP041693
• Organism: Bacillus amyloliquefaciens strain H

Toxin (Protein)

• Gene name: bsrG
• Uniprot ID: L8EAY0
• Locus tag: FOG69_RS10705
• Protein ID: WP_009967548.1
• Coordinates: 2101655..2101771 (+)
• Length: 39 a.a.

Antitoxin (RNA)

Gene name	as-bsrG
Locus tag	-
Coordinates	2101766..2101905 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FOG69_RS10675	2096792..2097052	+	261	WP_014472510.1	hypothetical protein	-
FOG69_RS10680	2097204..2098366	+	1163	Protein_2057	tetratricopeptide repeat protein	-
FOG69_RS10685	2098530..2099780	-	1251	WP_014470073.1	UV-damage repair protein uvrX	-
FOG69_RS10690	2099773..2100105	-	333	WP_014470072.1	YolD-like family protein	-
FOG69_RS10695	2100324..2100988	-	665	Protein_2060	sporulation protein YunB	-
FOG69_RS10700	2101223..2101426	-	204	WP_014470071.1	hypothetical protein	-
FOG69_RS10705	2101655..2101771	+	117	WP_009967548.1	type I toxin-antitoxin system toxin BsrG	Toxin
-	2101766..2101905	-	140	NuclAT_0	-	Antitoxin
-	2101766..2101905	-	140	NuclAT_0	-	Antitoxin
-	2101766..2101905	-	140	NuclAT_0	-	Antitoxin
-	2101766..2101905	-	140	NuclAT_0	-	Antitoxin
FOG69_RS10710	2102079..2102537	-	459	WP_014470070.1	SMI1/KNR4 family protein	-
FOG69_RS10715	2102550..2104436	-	1887	WP_014470069.1	HNH endonuclease	-
FOG69_RS10720	2104943..2105713	+	771	WP_014470068.1	hypothetical protein	-
FOG69_RS10725	2105757..2106191	-	435	WP_076982859.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1971172..2109227	138055

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-38)

Sequences

Toxin

Protein

• Length: 39 a.a.
• Molecular weight: 4336.39 Da
• Isoelectric Point: 10.1022

>T129014 WP_009967548.1 NZ_CP041693:2101655-2101771 [Bacillus amyloliquefaciens]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Nucleotide

• Length: 117 bp

>T129014 NZ_CP041693:2101655-2101771 [Bacillus amyloliquefaciens]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin

Nucleotide

• Length: 140 bp

>AT129014 NZ_CP041693:c2101905-2101766 [Bacillus amyloliquefaciens]
AAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCACCCCGGCTCTGTACAAAAAGCTGCCCATCAAAGGGCTTGCTCG
ATGTTGAATCTGCGTAGACCTAACCCTTTAAGGTTCCTAAGCTCAAGGGAAGGTCTATTT

Structures

Toxin

• AlphaFold DB: A0A7Z7EVU9

Antitoxin