Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 4235643..4236151 Replicon chromosome
Accession NZ_CP041692
Organism Microlunatus sp. KUDC0627

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag FOE78_RS19140 Protein ID WP_210415053.1
Coordinates 4235903..4236151 (+) Length 83 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FOE78_RS19135 Protein ID WP_143987696.1
Coordinates 4235643..4235894 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOE78_RS19110 4231373..4231792 - 420 WP_143987695.1 hypothetical protein -
FOE78_RS19120 4232781..4234199 + 1419 WP_210414671.1 IS21 family transposase -
FOE78_RS19125 4234202..4234675 + 474 WP_143984780.1 hypothetical protein -
FOE78_RS19130 4234672..4235442 + 771 WP_143984779.1 IS21-like element helper ATPase IstB -
FOE78_RS19135 4235643..4235894 + 252 WP_143987696.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FOE78_RS19140 4235903..4236151 + 249 WP_210415053.1 Txe/YoeB family addiction module toxin Toxin
FOE78_RS19145 4236472..4237041 + 570 WP_143987698.1 PadR family transcriptional regulator -
FOE78_RS19150 4237061..4238155 + 1095 WP_210414672.1 ABC transporter permease -
FOE78_RS19155 4238305..4238718 - 414 WP_143988938.1 helix-turn-helix transcriptional regulator -
FOE78_RS19160 4238758..4239390 + 633 WP_143987700.1 NAD(P)H:quinone oxidoreductase -
FOE78_RS19165 4239998..4240837 + 840 WP_210414673.1 alpha/beta fold hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4219813..4245660 25847


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(3-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 9756.09 Da        Isoelectric Point: 6.7233

>T129007 WP_210415053.1 NZ_CP041692:4235903-4236151 [Microlunatus sp. KUDC0627]
MAFDPNGWEDYLYWQTQDRKTLKRINQLIADVLRDPFAGIGKPEPLKHVLTGAWSRRIDEANRLVYYVTEEHIVILQARD
HY

Download         Length: 249 bp

>T129007 NZ_CP041692:4235903-4236151 [Microlunatus sp. KUDC0627]
CTGGCCTTCGACCCGAATGGGTGGGAGGACTACCTGTACTGGCAGACCCAGGACCGCAAGACACTCAAACGGATCAATCA
ACTCATCGCCGACGTGCTGCGGGACCCGTTCGCTGGCATCGGTAAGCCAGAGCCGCTGAAGCACGTCCTGACGGGCGCAT
GGTCACGCCGGATCGACGAAGCCAATCGCCTCGTCTACTACGTCACCGAGGAACACATCGTGATCTTGCAGGCTCGGGAT
CATTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9288.37 Da        Isoelectric Point: 4.5069

>AT129007 WP_143987696.1 NZ_CP041692:4235643-4235894 [Microlunatus sp. KUDC0627]
MVAITATDARKGLFGIIQEVNDDHTAVEVVSRHGNAVIMSKDDYDAMTETTYLLRNAANAERLLEAIERARRGEFEQHDL
LEA

Download         Length: 252 bp

>AT129007 NZ_CP041692:4235643-4235894 [Microlunatus sp. KUDC0627]
ATGGTCGCTATCACTGCAACTGATGCTCGCAAGGGTCTGTTCGGCATCATTCAGGAGGTGAATGATGACCACACCGCCGT
CGAGGTCGTCTCGCGGCACGGCAACGCAGTCATCATGTCCAAGGACGACTACGACGCGATGACCGAGACCACCTACCTGT
TGCGGAACGCCGCCAACGCAGAACGACTGCTTGAGGCGATCGAGCGTGCCCGGCGCGGCGAGTTCGAGCAGCATGATCTG
CTTGAAGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References