Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 650900..651455 Replicon chromosome
Accession NZ_CP041661
Organism Catenovulum sediminis strain WS1-A

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag FNT16_RS19860 Protein ID WP_143873927.1
Coordinates 651183..651455 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag FNT16_RS19855 Protein ID WP_143871992.1
Coordinates 650900..651190 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNT16_RS19835 646556..648193 + 1638 WP_143873767.1 IS1634 family transposase -
FNT16_RS20485 648242..648418 + 177 WP_185976775.1 hypothetical protein -
FNT16_RS19840 648463..648699 - 237 Protein_453 hypothetical protein -
FNT16_RS20490 648705..648860 - 156 WP_185976776.1 hypothetical protein -
FNT16_RS19845 648984..649463 - 480 WP_143873768.1 hypothetical protein -
FNT16_RS19850 649451..650662 - 1212 WP_143873769.1 hypothetical protein -
FNT16_RS19855 650900..651190 - 291 WP_143871992.1 helix-turn-helix domain-containing protein Antitoxin
FNT16_RS19860 651183..651455 - 273 WP_143873927.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FNT16_RS20495 651695..651871 + 177 WP_185976777.1 hypothetical protein -
FNT16_RS19865 652162..652734 - 573 WP_143873771.1 hypothetical protein -
FNT16_RS19870 652734..654152 - 1419 WP_143873773.1 hypothetical protein -
FNT16_RS19875 654149..654586 - 438 WP_143873775.1 hypothetical protein -
FNT16_RS19880 654598..655701 - 1104 WP_185976778.1 hypothetical protein -
FNT16_RS19885 655729..656241 - 513 WP_143872497.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(27-85)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-89)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10441.94 Da        Isoelectric Point: 8.3582

>T128960 WP_143873927.1 NZ_CP041661:c651455-651183 [Catenovulum sediminis]
MTGGEYKDLQEALITRPDKGAIIKNSNGIRKIRWTLEGRGKSGGVRVIYYWMTEDEQIYMLYAYPKSTQENLTDAQLKVM
KQIVEGWTHE

Download         Length: 273 bp

>T128960 NZ_CP041661:c651455-651183 [Catenovulum sediminis]
ATGACAGGTGGTGAATACAAAGACTTACAAGAAGCCCTAATCACTAGGCCAGATAAAGGGGCGATAATAAAAAACAGCAA
CGGGATCAGAAAAATCCGCTGGACACTCGAAGGTCGAGGAAAAAGTGGAGGAGTGCGTGTTATCTATTACTGGATGACAG
AAGATGAGCAGATATACATGCTGTACGCGTACCCAAAAAGTACACAAGAAAATTTAACCGATGCCCAATTAAAAGTTATG
AAACAGATAGTAGAGGGGTGGACACATGAATGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10662.31 Da        Isoelectric Point: 10.3403

>AT128960 WP_143871992.1 NZ_CP041661:c651190-650900 [Catenovulum sediminis]
MNDEMFKELVQSMEQAGDIMKGKAKPSRVTVFAEPEVKAIRAKTGLSQSRFADIVGVSKRTLENWEQGRRHPTGPARALL
KILDADPQYALKALHG

Download         Length: 291 bp

>AT128960 NZ_CP041661:c651190-650900 [Catenovulum sediminis]
ATGAATGATGAAATGTTTAAAGAACTCGTGCAGAGCATGGAGCAAGCTGGCGATATAATGAAAGGTAAAGCTAAACCATC
ACGTGTAACCGTGTTTGCAGAGCCTGAAGTTAAAGCCATTAGAGCGAAAACAGGTTTAAGCCAAAGCCGCTTTGCAGACA
TAGTAGGCGTTAGCAAACGAACACTAGAAAACTGGGAACAAGGTCGCAGGCACCCAACAGGGCCAGCAAGAGCCTTACTG
AAAATACTGGATGCTGATCCACAATATGCACTAAAAGCATTGCATGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References