Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 571994..572694 Replicon chromosome
Accession NZ_CP041661
Organism Catenovulum sediminis strain WS1-A

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag FNT16_RS19550 Protein ID WP_143872834.1
Coordinates 571994..572386 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag FNT16_RS19555 Protein ID WP_143870009.1
Coordinates 572401..572694 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNT16_RS19535 568005..569684 + 1680 WP_143873681.1 sulfatase-like hydrolase/transferase -
FNT16_RS19540 569828..570409 + 582 WP_143873683.1 class I SAM-dependent methyltransferase -
FNT16_RS19545 570694..571610 - 917 Protein_392 Abi family protein -
FNT16_RS19550 571994..572386 - 393 WP_143872834.1 type II toxin-antitoxin system YafO family toxin Toxin
FNT16_RS19555 572401..572694 - 294 WP_143870009.1 hypothetical protein Antitoxin
FNT16_RS19560 573026..573262 - 237 WP_143873685.1 carboxymuconolactone decarboxylase family protein -
FNT16_RS19565 573273..573437 + 165 WP_143873920.1 helix-turn-helix domain-containing protein -
FNT16_RS19570 573434..574333 - 900 WP_143873686.1 LysR family transcriptional regulator -
FNT16_RS19575 574527..575165 + 639 WP_143873688.1 glutathione S-transferase -
FNT16_RS19580 575171..576214 + 1044 WP_143873690.1 pyridoxamine 5'-phosphate oxidase family protein -
FNT16_RS19585 576241..576672 + 432 WP_143873692.1 nuclear transport factor 2 family protein -
FNT16_RS19590 576725..577591 + 867 WP_143873693.1 bile acid:sodium symporter family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(27-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 15127.21 Da        Isoelectric Point: 6.9109

>T128959 WP_143872834.1 NZ_CP041661:c572386-571994 [Catenovulum sediminis]
IRVFKHKILIDSLTESELQSLTKDFRHYKETGQKPDFFGRDEAYNHPDTLPILKSEEVKHIHLAASDAPFLSSIQFYQTS
DKHLVYCQGWNDLSCFLLIAILAPDAHEQARNRTIMHNLGLIAEKFRQQF

Download         Length: 393 bp

>T128959 NZ_CP041661:c572386-571994 [Catenovulum sediminis]
ATTAGAGTTTTTAAGCATAAGATCTTAATTGATTCACTTACTGAAAGTGAGCTTCAATCTTTGACTAAAGACTTTAGACA
CTATAAAGAAACAGGTCAAAAACCAGATTTTTTTGGCCGAGATGAAGCTTATAATCATCCCGATACATTACCGATCTTGA
AGTCAGAGGAAGTTAAGCACATTCACTTAGCTGCTAGTGATGCTCCGTTCTTAAGTTCTATCCAATTTTACCAAACGAGC
GATAAGCACTTAGTGTATTGTCAAGGTTGGAATGACCTTAGTTGTTTTCTGTTAATCGCCATCCTTGCCCCTGACGCTCA
TGAGCAAGCTCGTAATCGAACTATCATGCATAACTTGGGTTTGATAGCTGAAAAATTTCGGCAGCAATTCTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10664.03 Da        Isoelectric Point: 4.5037

>AT128959 WP_143870009.1 NZ_CP041661:c572694-572401 [Catenovulum sediminis]
MKTSTIYAEKAVSSSEARKHFKDCLSGEPVVVLSNNEPAGYMMSATFFEGLMKALEGKNADSVSSFRPMSARLEVISHLN
AQALTELDESILDEFQE

Download         Length: 294 bp

>AT128959 NZ_CP041661:c572694-572401 [Catenovulum sediminis]
ATGAAAACAAGTACAATCTATGCAGAAAAAGCAGTGTCATCAAGCGAAGCTAGAAAACATTTTAAAGATTGTTTATCAGG
GGAGCCAGTTGTAGTTTTATCGAACAATGAGCCTGCTGGTTATATGATGAGCGCCACTTTTTTTGAAGGGCTAATGAAAG
CTTTGGAGGGCAAAAATGCTGACTCTGTTTCATCATTTAGGCCAATGAGTGCTCGCTTAGAAGTCATTTCTCATCTGAAT
GCTCAAGCATTAACAGAGCTTGATGAAAGTATTTTGGATGAGTTTCAAGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References