Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4084687..4085279 Replicon chromosome
Accession NZ_CP041660
Organism Catenovulum sediminis strain WS1-A

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag FNT16_RS17465 Protein ID WP_143872793.1
Coordinates 4085001..4085279 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag FNT16_RS17460 Protein ID WP_143872792.1
Coordinates 4084687..4085001 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNT16_RS17425 4079898..4080269 - 372 WP_143873020.1 hypothetical protein -
FNT16_RS17430 4080393..4080617 - 225 WP_143872787.1 SIP domain-containing protein -
FNT16_RS20435 4080562..4080792 + 231 WP_185976764.1 hypothetical protein -
FNT16_RS17435 4080978..4081808 + 831 WP_143872788.1 tyrosine-type recombinase/integrase -
FNT16_RS17440 4081812..4082897 + 1086 WP_143872789.1 IS91 family transposase -
FNT16_RS17445 4083223..4083594 + 372 WP_143872790.1 DoxX-like family protein -
FNT16_RS17450 4083826..4084257 - 432 WP_143872791.1 NUDIX pyrophosphatase -
FNT16_RS17455 4084393..4084542 - 150 WP_185976638.1 hypothetical protein -
FNT16_RS17460 4084687..4085001 - 315 WP_143872792.1 HigA family addiction module antidote protein Antitoxin
FNT16_RS17465 4085001..4085279 - 279 WP_143872793.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FNT16_RS17470 4085554..4085961 - 408 WP_143872794.1 hypothetical protein -
FNT16_RS17480 4086369..4087064 - 696 WP_143872795.1 HNH endonuclease -
FNT16_RS17485 4087168..4087521 - 354 WP_185976639.1 hypothetical protein -
FNT16_RS17495 4087963..4088616 - 654 WP_143872797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(3-92)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(3-83)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10836.54 Da        Isoelectric Point: 9.9436

>T128954 WP_143872793.1 NZ_CP041660:c4085279-4085001 [Catenovulum sediminis]
MIKSFIHKGLEKFYATGKTAGIQKKHEKKIRLILANLDQAEVPDDMDLPGLFMHKLKGDRKEIWSVRVSGNWRITYRFTG
RDVEIVNYEDYH

Download         Length: 279 bp

>T128954 NZ_CP041660:c4085279-4085001 [Catenovulum sediminis]
ATGATTAAAAGTTTCATTCATAAAGGCCTAGAAAAGTTTTACGCAACTGGCAAAACCGCCGGAATACAAAAAAAGCATGA
AAAGAAAATTCGTTTGATTTTAGCTAATTTAGATCAGGCTGAAGTTCCTGACGATATGGACTTACCGGGCTTATTTATGC
ATAAACTTAAAGGCGATAGAAAAGAAATATGGTCTGTTCGAGTAAGCGGTAATTGGCGAATCACCTACCGTTTCACCGGA
CGGGATGTTGAAATAGTAAATTATGAGGATTATCACTAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11728.59 Da        Isoelectric Point: 9.5138

>AT128954 WP_143872792.1 NZ_CP041660:c4085001-4084687 [Catenovulum sediminis]
MSMHNPAHPGEILKELVIEPMGVTITDVAKHLDVSRKTLSKVLNAKGSITPEMAVRLELAFGKPSADHWLKLQNAFDLWQ
MRQTQSTLHVSPYNLQLAYSTYNK

Download         Length: 315 bp

>AT128954 NZ_CP041660:c4085001-4084687 [Catenovulum sediminis]
ATGTCTATGCATAATCCAGCACACCCAGGCGAAATTCTAAAAGAATTAGTAATTGAGCCTATGGGAGTCACGATAACAGA
TGTAGCGAAACATTTAGATGTAAGTCGCAAGACACTTTCAAAAGTTTTAAATGCAAAAGGCTCAATTACTCCAGAGATGG
CGGTAAGGTTGGAGCTTGCTTTTGGAAAGCCTTCTGCCGATCATTGGTTAAAGCTTCAGAATGCATTTGACCTTTGGCAA
ATGAGGCAAACCCAAAGCACCTTACATGTGTCTCCATATAACTTACAATTAGCGTATTCGACGTATAATAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References