Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 1734911..1735502 Replicon chromosome
Accession NZ_CP041660
Organism Catenovulum sediminis strain WS1-A

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag FNT16_RS07010 Protein ID WP_143870916.1
Coordinates 1734911..1735222 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag FNT16_RS07015 Protein ID WP_143870917.1
Coordinates 1735215..1735502 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNT16_RS06980 1730647..1731129 + 483 WP_143870912.1 hypothetical protein -
FNT16_RS06985 1731438..1732328 + 891 WP_143870913.1 hypothetical protein -
FNT16_RS06990 1732408..1733070 - 663 Protein_1353 group II intron reverse transcriptase/maturase -
FNT16_RS20365 1733133..1733306 - 174 WP_185976718.1 hypothetical protein -
FNT16_RS06995 1733872..1734204 + 333 WP_143870914.1 type II toxin-antitoxin system RelE/ParE family toxin -
FNT16_RS07000 1734191..1734505 + 315 WP_071979346.1 DNA-binding transcriptional regulator -
FNT16_RS07010 1734911..1735222 + 312 WP_143870916.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FNT16_RS07015 1735215..1735502 + 288 WP_143870917.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
FNT16_RS07025 1735998..1736294 + 297 WP_143870918.1 HigA family addiction module antidote protein -
FNT16_RS07030 1736665..1737159 + 495 WP_143870919.1 ATP-binding protein -
FNT16_RS07035 1737284..1737709 + 426 WP_143870920.1 GFA family protein -
FNT16_RS07040 1738299..1738922 + 624 WP_143872907.1 PEP-CTERM sorting domain-containing protein -
FNT16_RS07045 1739775..1740269 + 495 WP_143870921.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(41-85)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11704.44 Da        Isoelectric Point: 9.2507

>T128951 WP_143870916.1 NZ_CP041660:1734911-1735222 [Catenovulum sediminis]
MVFIETSFFTKLLPDYLSDDEYRGLQSYLLQKPDVGDIVKGSGGVRKVRWASSGKGKSGGIRVVYYWKKAEHEIWMLTMY
SKSERATIAGHVLKQIAEAIENE

Download         Length: 312 bp

>T128951 NZ_CP041660:1734911-1735222 [Catenovulum sediminis]
ATGGTCTTTATAGAAACAAGCTTCTTTACAAAACTGCTACCAGATTATTTATCGGATGATGAATATCGTGGTCTGCAATC
TTACCTTCTTCAAAAGCCAGATGTCGGTGATATTGTAAAAGGCTCTGGTGGTGTCAGGAAGGTTAGATGGGCTTCTTCAG
GCAAAGGTAAAAGTGGTGGCATACGTGTTGTTTACTATTGGAAGAAGGCTGAACATGAGATATGGATGCTCACTATGTAT
AGTAAATCGGAGCGGGCTACTATCGCGGGTCATGTGTTAAAACAAATAGCAGAGGCAATCGAAAATGAGTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10632.22 Da        Isoelectric Point: 10.2671

>AT128951 WP_143870917.1 NZ_CP041660:1735215-1735502 [Catenovulum sediminis]
MSNRDIGSEILAGINEIKEYKKGKVSLRSNELSEPSAPQVIRSKLKMSQVMFAGLLGVSTRTLQDWEQGRRNPQGPAVAL
LRIAEQHPEIFSELR

Download         Length: 288 bp

>AT128951 NZ_CP041660:1735215-1735502 [Catenovulum sediminis]
ATGAGTAACAGAGATATAGGTTCCGAAATTCTTGCAGGTATAAATGAGATTAAGGAATATAAAAAGGGAAAGGTTTCTCT
ACGTAGTAACGAATTAAGTGAGCCATCAGCGCCACAGGTAATTCGTTCTAAATTGAAAATGTCTCAGGTCATGTTTGCAG
GTTTACTCGGTGTCAGCACAAGAACTTTGCAGGACTGGGAACAAGGCCGCAGAAACCCTCAAGGGCCAGCAGTTGCATTA
TTGCGGATAGCTGAGCAACACCCTGAAATTTTTAGCGAATTGAGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References