Detailed information of TA system TA128947

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yafN-yafO (relBE)/YafO-YafN
• Location: 545444..546144
• Replicon: chromosome
• Accession: NZ_CP041660
• Organism: Catenovulum sediminis strain WS1-A

Toxin (Protein)

• Gene name: yafO
• Uniprot ID: -
• Locus tag: FNT16_RS02145
• Protein ID: WP_143872834.1
• Coordinates: 545752..546144 (+)
• Length: 131 a.a.

Antitoxin (Protein)

• Gene name: yafN
• Uniprot ID: -
• Locus tag: FNT16_RS02140
• Protein ID: WP_143870009.1
• Coordinates: 545444..545737 (+)
• Length: 98 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FNT16_RS02125	540672..543953	+	3282	WP_143870007.1	hypothetical protein	-
FNT16_RS02130	544061..544626	-	566	Protein_412	PIN domain-containing protein	-
FNT16_RS02135	544632..545084	-	453	WP_143870008.1	helix-turn-helix domain-containing protein	-
FNT16_RS02140	545444..545737	+	294	WP_143870009.1	hypothetical protein	Antitoxin
FNT16_RS02145	545752..546144	+	393	WP_143872834.1	type II toxin-antitoxin system YafO family toxin	Toxin
FNT16_RS02150	546327..548345	-	2019	WP_143872835.1	glycoside hydrolase family 32 protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin YafO (27-128)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 131 a.a.
• Molecular weight: 15127.21 Da
• Isoelectric Point: 6.9109

>T128947 WP_143872834.1 NZ_CP041660:545752-546144 [Catenovulum sediminis]
IRVFKHKILIDSLTESELQSLTKDFRHYKETGQKPDFFGRDEAYNHPDTLPILKSEEVKHIHLAASDAPFLSSIQFYQTS
DKHLVYCQGWNDLSCFLLIAILAPDAHEQARNRTIMHNLGLIAEKFRQQF

Nucleotide

• Length: 393 bp

>T128947 NZ_CP041660:545752-546144 [Catenovulum sediminis]
ATTAGAGTTTTTAAGCATAAGATCTTAATTGATTCACTTACTGAAAGTGAGCTTCAATCTTTGACTAAAGACTTTAGACA
CTATAAAGAAACAGGTCAAAAACCAGATTTTTTTGGTCGAGATGAAGCTTATAATCATCCCGATACATTACCGATCTTGA
AGTCAGAGGAAGTTAAGCACATTCACTTAGCTGCTAGTGATGCTCCGTTCTTAAGTTCTATCCAATTTTACCAAACGAGC
GATAAGCACCTAGTGTATTGTCAAGGTTGGAATGACCTTAGTTGTTTTCTGTTAATCGCCATCCTTGCCCCTGACGCTCA
TGAGCAAGCTCGTAATCGAACTATCATGCATAACTTGGGTTTGATAGCTGAAAAATTTCGGCAGCAATTCTAA

Antitoxin

Protein

• Length: 98 a.a.
• Molecular weight: 10664.03 Da
• Isoelectric Point: 4.5037

>AT128947 WP_143870009.1 NZ_CP041660:545444-545737 [Catenovulum sediminis]
MKTSTIYAEKAVSSSEARKHFKDCLSGEPVVVLSNNEPAGYMMSATFFEGLMKALEGKNADSVSSFRPMSARLEVISHLN
AQALTELDESILDEFQE

Nucleotide

• Length: 294 bp

>AT128947 NZ_CP041660:545444-545737 [Catenovulum sediminis]
ATGAAAACAAGTACAATCTATGCAGAAAAAGCAGTGTCATCAAGCGAAGCTAGAAAGCATTTTAAAGATTGTTTATCAGG
GGAGCCAGTCGTAGTTTTATCGAACAATGAGCCTGCTGGTTATATGATGAGCGCCACTTTTTTTGAAGGGCTAATGAAAG
CTTTGGAGGGCAAAAATGCTGACTCTGTTTCATCATTTAGGCCAATGAGTGCTCGCTTAGAAGTCATTTCTCATCTGAAT
GCTCAAGCATTAACAGAGCTTGATGAAAGTATTTTGGATGAGTTTCAAGAGTGA