Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-YefM |
Location | 3285072..3285574 | Replicon | chromosome |
Accession | NZ_CP041422 | ||
Organism | Escherichia coli strain STEC409 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | - |
Locus tag | FNE86_RS16260 | Protein ID | WP_001471733.1 |
Coordinates | 3285072..3285326 (-) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | S1Q063 |
Locus tag | FNE86_RS16265 | Protein ID | WP_001259255.1 |
Coordinates | 3285323..3285574 (-) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FNE86_RS16240 | 3281565..3282923 | - | 1359 | WP_000019197.1 | putrescine/proton symporter PlaP | - |
FNE86_RS16245 | 3282913..3282975 | - | 63 | WP_010723108.1 | membrane protein YoeI | - |
FNE86_RS16250 | 3283190..3284119 | - | 930 | WP_001374016.1 | LysR family transcriptional regulator | - |
FNE86_RS16255 | 3284165..3284989 | - | 825 | WP_000754737.1 | SDR family oxidoreductase | - |
FNE86_RS16260 | 3285072..3285326 | - | 255 | WP_001471733.1 | type II toxin-antitoxin system mRNA interferase toxin YoeB | Toxin |
FNE86_RS16265 | 3285323..3285574 | - | 252 | WP_001259255.1 | YoeB-YefM toxin-antitoxin system antitoxin YefM | Antitoxin |
FNE86_RS16270 | 3285857..3285907 | + | 51 | WP_001364200.1 | his operon leader peptide | - |
FNE86_RS16275 | 3286053..3286952 | + | 900 | WP_001374031.1 | ATP phosphoribosyltransferase | - |
FNE86_RS16280 | 3286958..3288262 | + | 1305 | WP_001748534.1 | histidinol dehydrogenase | - |
FNE86_RS16285 | 3288259..3289329 | + | 1071 | WP_001374029.1 | histidinol-phosphate transaminase | - |
FNE86_RS16290 | 3289329..3290396 | + | 1068 | WP_001374028.1 | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 10195.64 Da Isoelectric Point: 8.0353
>T128400 WP_001471733.1 NZ_CP041422:c3285326-3285072 [Escherichia coli]
VKLIWSEESWDDYLYWQETDKRIVKKINELIKDIRRTPFEGKGKPEPLKHNLSGFWSRRITEEHRLVYAVTDDSLLIAAC
RYHY
VKLIWSEESWDDYLYWQETDKRIVKKINELIKDIRRTPFEGKGKPEPLKHNLSGFWSRRITEEHRLVYAVTDDSLLIAAC
RYHY
Download Length: 255 bp
>T128400 NZ_CP041422:c3285326-3285072 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATATCCGCAGAACACCATTTGAAGGTAAGGGGAAACCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATATCCGCAGAACACCATTTGAAGGTAAGGGGAAACCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9307.58 Da Isoelectric Point: 4.7954
>AT128400 WP_001259255.1 NZ_CP041422:c3285574-3285323 [Escherichia coli]
MRTISYSEARQNLSATMMKAVEDHAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANARRLMDSIDSLKSGKGTEKD
IIE
MRTISYSEARQNLSATMMKAVEDHAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANARRLMDSIDSLKSGKGTEKD
IIE
Download Length: 252 bp
>AT128400 NZ_CP041422:c3285574-3285323 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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