Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | hok-sok/- |
Location | 17477..17731 | Replicon | plasmid pSTEC711_5 |
Accession | NZ_CP041421 | ||
Organism | Escherichia coli strain STEC711 |
Toxin (Protein)
Gene name | srnB | Uniprot ID | - |
Locus tag | FNE87_RS24815 | Protein ID | WP_178086280.1 |
Coordinates | 17525..17731 (+) | Length | 69 a.a. |
Antitoxin (RNA)
Gene name | srnC | ||
Locus tag | - | ||
Coordinates | 17477..17538 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FNE87_RS24790 | 14791..15537 | + | 747 | WP_161620439.1 | conjugal transfer pilus acetylase TraX | - |
FNE87_RS24795 | 15592..16152 | + | 561 | WP_000139366.1 | fertility inhibition protein FinO | - |
FNE87_RS24800 | 16287..16499 | + | 213 | WP_112832261.1 | hypothetical protein | - |
FNE87_RS24805 | 16743..17107 | + | 365 | Protein_14 | thermonuclease family protein | - |
FNE87_RS24810 | 17107..17300 | + | 194 | Protein_15 | DUF2726 domain-containing protein | - |
- | 17477..17538 | - | 62 | NuclAT_0 | - | Antitoxin |
- | 17477..17538 | - | 62 | NuclAT_0 | - | Antitoxin |
- | 17477..17538 | - | 62 | NuclAT_0 | - | Antitoxin |
- | 17477..17538 | - | 62 | NuclAT_0 | - | Antitoxin |
FNE87_RS24815 | 17525..17731 | + | 207 | WP_178086280.1 | type I toxin-antitoxin system Hok family toxin | Toxin |
FNE87_RS24820 | 18014..18262 | + | 249 | WP_000083838.1 | replication regulatory protein RepA | - |
FNE87_RS24825 | 18505..18579 | + | 75 | WP_001367777.1 | RepA leader peptide Tap | - |
FNE87_RS24830 | 18572..19429 | + | 858 | WP_033562000.1 | incFII family plasmid replication initiator RepA | - |
FNE87_RS24840 | 20343..20612 | + | 270 | WP_000079941.1 | hypothetical protein | - |
FNE87_RS24845 | 20609..20890 | + | 282 | WP_000969996.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
FNE87_RS24850 | 21154..22326 | + | 1173 | WP_096934598.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Conjugative plasmid | - | - | 1..82344 | 82344 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 69 a.a. Molecular weight: 7782.27 Da Isoelectric Point: 8.6543
>T128378 WP_178086280.1 NZ_CP041421:17525-17731 [Escherichia coli]
MKYLNTTDCSLFFAERSKCMTKYALIGLLAVCATVLCFSLIFRERLCELNIHRGNTVVQVTLAYEARK
MKYLNTTDCSLFFAERSKCMTKYALIGLLAVCATVLCFSLIFRERLCELNIHRGNTVVQVTLAYEARK
Download Length: 207 bp
>T128378 NZ_CP041421:17525-17731 [Escherichia coli]
ATGAAGTACCTTAACACTACTGATTGTAGCCTCTTCTTTGCTGAGAGGTCAAAGTGTATGACGAAATATGCCCTTATCGG
GTTGCTCGCCGTGTGCGCCACGGTGTTGTGTTTTTCACTGATATTCAGGGAACGGTTATGTGAACTGAATATTCACAGGG
GAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA
ATGAAGTACCTTAACACTACTGATTGTAGCCTCTTCTTTGCTGAGAGGTCAAAGTGTATGACGAAATATGCCCTTATCGG
GTTGCTCGCCGTGTGCGCCACGGTGTTGTGTTTTTCACTGATATTCAGGGAACGGTTATGTGAACTGAATATTCACAGGG
GAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA
Antitoxin
Download Length: 62 bp
>AT128378 NZ_CP041421:c17538-17477 [Escherichia coli]
TTAAGGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT
TTAAGGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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