Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) hok-sok/-
Location 17477..17731 Replicon plasmid pSTEC711_5
Accession NZ_CP041421
Organism Escherichia coli strain STEC711

Toxin (Protein)


Gene name srnB Uniprot ID -
Locus tag FNE87_RS24815 Protein ID WP_178086280.1
Coordinates 17525..17731 (+) Length 69 a.a.

Antitoxin (RNA)


Gene name srnC
Locus tag -
Coordinates 17477..17538 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNE87_RS24790 14791..15537 + 747 WP_161620439.1 conjugal transfer pilus acetylase TraX -
FNE87_RS24795 15592..16152 + 561 WP_000139366.1 fertility inhibition protein FinO -
FNE87_RS24800 16287..16499 + 213 WP_112832261.1 hypothetical protein -
FNE87_RS24805 16743..17107 + 365 Protein_14 thermonuclease family protein -
FNE87_RS24810 17107..17300 + 194 Protein_15 DUF2726 domain-containing protein -
- 17477..17538 - 62 NuclAT_0 - Antitoxin
- 17477..17538 - 62 NuclAT_0 - Antitoxin
- 17477..17538 - 62 NuclAT_0 - Antitoxin
- 17477..17538 - 62 NuclAT_0 - Antitoxin
FNE87_RS24815 17525..17731 + 207 WP_178086280.1 type I toxin-antitoxin system Hok family toxin Toxin
FNE87_RS24820 18014..18262 + 249 WP_000083838.1 replication regulatory protein RepA -
FNE87_RS24825 18505..18579 + 75 WP_001367777.1 RepA leader peptide Tap -
FNE87_RS24830 18572..19429 + 858 WP_033562000.1 incFII family plasmid replication initiator RepA -
FNE87_RS24840 20343..20612 + 270 WP_000079941.1 hypothetical protein -
FNE87_RS24845 20609..20890 + 282 WP_000969996.1 type II toxin-antitoxin system RelE/ParE family toxin -
FNE87_RS24850 21154..22326 + 1173 WP_096934598.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..82344 82344


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-64)


Sequences


Toxin        


Download         Length: 69 a.a.        Molecular weight: 7782.27 Da        Isoelectric Point: 8.6543

>T128378 WP_178086280.1 NZ_CP041421:17525-17731 [Escherichia coli]
MKYLNTTDCSLFFAERSKCMTKYALIGLLAVCATVLCFSLIFRERLCELNIHRGNTVVQVTLAYEARK

Download         Length: 207 bp

>T128378 NZ_CP041421:17525-17731 [Escherichia coli]
ATGAAGTACCTTAACACTACTGATTGTAGCCTCTTCTTTGCTGAGAGGTCAAAGTGTATGACGAAATATGCCCTTATCGG
GTTGCTCGCCGTGTGCGCCACGGTGTTGTGTTTTTCACTGATATTCAGGGAACGGTTATGTGAACTGAATATTCACAGGG
GAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 62 bp

>AT128378 NZ_CP041421:c17538-17477 [Escherichia coli]
TTAAGGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References