Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1868203..1868744 Replicon chromosome
Accession NZ_CP041348
Organism Komagataeibacter xylinus strain CGMCC 17276

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag FMA36_RS08925 Protein ID WP_159262040.1
Coordinates 1868475..1868744 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FMA36_RS08920 Protein ID WP_159262039.1
Coordinates 1868203..1868478 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FMA36_RS08895 1863860..1865392 + 1533 WP_159262036.1 glucose-6-phosphate dehydrogenase -
FMA36_RS08900 1865451..1866260 + 810 WP_159262037.1 Cof-type HAD-IIB family hydrolase -
FMA36_RS08905 1866253..1867002 + 750 WP_159263796.1 6-phosphogluconolactonase -
FMA36_RS08910 1867080..1867784 + 705 WP_159262038.1 ribose-5-phosphate isomerase RpiA -
FMA36_RS08915 1867962..1868150 + 189 WP_159263798.1 conjugal transfer protein TraA -
FMA36_RS08920 1868203..1868478 + 276 WP_159262039.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FMA36_RS08925 1868475..1868744 + 270 WP_159262040.1 Txe/YoeB family addiction module toxin Toxin
FMA36_RS08930 1868757..1868921 + 165 WP_159262041.1 hypothetical protein -
FMA36_RS08935 1868884..1870118 + 1235 WP_159261584.1 IS3 family transposase -
FMA36_RS08940 1870476..1870664 + 189 WP_159262042.1 hypothetical protein -
FMA36_RS08945 1870661..1872025 + 1365 WP_206065061.1 amidohydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1869366..1870118 752


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10535.86 Da        Isoelectric Point: 8.0801

>T128123 WP_159262040.1 NZ_CP041348:1868475-1868744 [Komagataeibacter xylinus]
VKVVFHEDGWEDYLSWFRSDNAVLEKANALIEDVRRHPFQGLGKPEPLKGQLSGWWSRRITGEHRLVYRVQGRAGEDQRI
EIAQCRFHY

Download         Length: 270 bp

>T128123 NZ_CP041348:1868475-1868744 [Komagataeibacter xylinus]
GTGAAAGTCGTTTTTCACGAAGATGGCTGGGAAGATTATCTTTCGTGGTTCCGGTCAGACAATGCGGTTCTTGAGAAGGC
CAATGCCCTGATCGAGGATGTAAGGCGACATCCATTTCAGGGGCTGGGCAAGCCGGAACCGCTGAAAGGTCAGCTTTCCG
GGTGGTGGTCCCGTCGGATTACGGGAGAACATCGTCTGGTCTACCGGGTTCAGGGGCGTGCGGGGGAGGATCAGCGGATC
GAGATTGCCCAATGCCGGTTTCATTACTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10256.49 Da        Isoelectric Point: 4.8550

>AT128123 WP_159262039.1 NZ_CP041348:1868203-1868478 [Komagataeibacter xylinus]
MTCVSYTDLRQNLAHYLDEAVNSRAPIIVTRKTGKGSVVLMSEEEFSGWQETVHLLSSPRNAERLLRSIRDIERGAATER
DLLEPQDEPSA

Download         Length: 276 bp

>AT128123 NZ_CP041348:1868203-1868478 [Komagataeibacter xylinus]
ATGACCTGTGTTTCCTATACCGACCTGCGCCAGAATCTGGCGCATTATCTGGATGAAGCCGTAAACAGCCGCGCGCCGAT
TATTGTGACCCGCAAGACCGGGAAAGGCAGTGTCGTGCTGATGTCGGAAGAAGAATTCTCCGGCTGGCAGGAGACCGTGC
ATCTCCTGAGCAGCCCGCGCAACGCGGAGAGGCTGTTGCGGAGCATTCGTGACATTGAGCGTGGGGCAGCGACCGAGCGT
GATCTTCTGGAGCCGCAGGATGAGCCGTCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References