Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 271865..272087 Replicon chromosome
Accession NZ_CP041304
Organism Escherichia coli strain MSHS 133

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag FK544_RS25640 Protein ID WP_001295224.1
Coordinates 271980..272087 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 271865..271931 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FK544_RS02345 267253..268236 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
FK544_RS02350 268233..269237 + 1005 WP_000107036.1 dipeptide ABC transporter ATP-binding subunit DppF -
FK544_RS02355 269267..270538 - 1272 WP_001318103.1 amino acid permease -
FK544_RS02365 271014..271121 + 108 WP_000170738.1 type I toxin-antitoxin system toxin Ldr family protein -
FK544_RS02375 271497..271604 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
- 271865..271931 - 67 - - Antitoxin
FK544_RS25640 271980..272087 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
FK544_RS02395 272463..272570 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
FK544_RS02400 272657..274336 - 1680 WP_001562264.1 cellulose biosynthesis protein BcsG -
FK544_RS02405 274333..274524 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
FK544_RS02410 274521..276092 - 1572 WP_141841192.1 cellulose biosynthesis protein BcsE -
FK544_RS02415 276365..276553 + 189 WP_001063315.1 YhjR family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T128017 WP_001295224.1 NZ_CP041304:271980-272087 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T128017 NZ_CP041304:271980-272087 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT128017 NZ_CP041304:c271931-271865 [Escherichia coli]
GTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7

Antitoxin

Download structure file

References