Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
| Location | 5008..5665 | Replicon | plasmid pSH11G0791 |
| Accession | NZ_CP041172 | ||
| Organism | Salmonella enterica subsp. enterica serovar Thompson strain SH11G0791 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | U3PDC3 |
| Locus tag | FKO09_RS23385 | Protein ID | WP_000270043.1 |
| Coordinates | 5008..5358 (+) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | FKO09_RS23390 | Protein ID | WP_000124640.1 |
| Coordinates | 5363..5665 (+) | Length | 101 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FKO09_RS23330 | 319..498 | + | 180 | Protein_0 | helix-turn-helix transcriptional regulator | - |
| FKO09_RS23335 | 563..1267 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| FKO09_RS23345 | 1482..1979 | - | 498 | WP_000062185.1 | hypothetical protein | - |
| FKO09_RS23350 | 1982..2470 | - | 489 | WP_001273096.1 | DUF1643 domain-containing protein | - |
| FKO09_RS23355 | 2567..2902 | + | 336 | WP_000683476.1 | hypothetical protein | - |
| FKO09_RS23360 | 2917..3387 | - | 471 | WP_001281821.1 | hypothetical protein | - |
| FKO09_RS23365 | 3380..3751 | - | 372 | WP_000516916.1 | hypothetical protein | - |
| FKO09_RS23370 | 3762..3956 | - | 195 | WP_000343597.1 | hypothetical protein | - |
| FKO09_RS23380 | 4297..4845 | - | 549 | WP_001061574.1 | transcriptional regulator | - |
| FKO09_RS23385 | 5008..5358 | + | 351 | WP_000270043.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| FKO09_RS23390 | 5363..5665 | + | 303 | WP_000124640.1 | XRE family transcriptional regulator | Antitoxin |
| FKO09_RS23395 | 5692..5985 | - | 294 | WP_001239997.1 | chromosome segregation protein ParM | - |
| FKO09_RS23400 | 6073..6345 | - | 273 | WP_001043047.1 | HU family DNA-binding protein | - |
| FKO09_RS23405 | 6403..6930 | - | 528 | WP_001236377.1 | thermonuclease family protein | - |
| FKO09_RS23415 | 7161..8018 | - | 858 | WP_001167032.1 | hypothetical protein | - |
| FKO09_RS23420 | 8005..8235 | - | 231 | WP_000972663.1 | hypothetical protein | - |
| FKO09_RS23425 | 8235..8753 | - | 519 | WP_000210756.1 | nitrite reductase | - |
| FKO09_RS23430 | 8750..9196 | - | 447 | WP_000919345.1 | Fe3+-siderophore ABC transporter permease | - |
| FKO09_RS23435 | 9196..9555 | - | 360 | WP_000422768.1 | hypothetical protein | - |
| FKO09_RS23440 | 9612..10040 | - | 429 | WP_000591074.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..153516 | 153516 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 15014.38 Da Isoelectric Point: 12.8644
>T127756 WP_000270043.1 NZ_CP041172:5008-5358 [Salmonella enterica subsp. enterica serovar Thompson]
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Download Length: 351 bp
>T127756 NZ_CP041172:5008-5358 [Salmonella enterica subsp. enterica serovar Thompson]
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Antitoxin
Download Length: 101 a.a. Molecular weight: 12963.60 Da Isoelectric Point: 12.8000
>AT127756 WP_000124640.1 NZ_CP041172:5363-5665 [Salmonella enterica subsp. enterica serovar Thompson]
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Download Length: 303 bp
>AT127756 NZ_CP041172:5363-5665 [Salmonella enterica subsp. enterica serovar Thompson]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|