Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 4115209..4115816 Replicon chromosome
Accession NZ_CP041046
Organism Luteibacter pinisoli strain MAH-14

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag FIV34_RS18740 Protein ID WP_139985020.1
Coordinates 4115493..4115816 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag FIV34_RS18735 Protein ID WP_139985019.1
Coordinates 4115209..4115496 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIV34_RS18705 4110757..4111512 + 756 WP_139986085.1 alpha/beta fold hydrolase -
FIV34_RS18710 4111513..4112430 - 918 WP_139985015.1 heme o synthase -
FIV34_RS18715 4112427..4113572 - 1146 WP_139985016.1 COX15/CtaA family protein -
FIV34_RS18720 4113572..4114132 - 561 WP_139985017.1 hypothetical protein -
FIV34_RS18725 4114129..4114863 - 735 WP_139985018.1 SURF1 family protein -
FIV34_RS18730 4114905..4115141 + 237 WP_211352661.1 twin transmembrane helix small protein -
FIV34_RS18735 4115209..4115496 - 288 WP_139985019.1 helix-turn-helix domain-containing protein Antitoxin
FIV34_RS18740 4115493..4115816 - 324 WP_139985020.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FIV34_RS18745 4116038..4116928 - 891 WP_139985021.1 cytochrome c oxidase subunit 3 -
FIV34_RS18750 4117090..4118703 - 1614 WP_139985022.1 cytochrome c oxidase subunit I -
FIV34_RS18755 4118755..4119657 - 903 WP_139985023.1 cytochrome c oxidase subunit II -
FIV34_RS18760 4119677..4120159 - 483 WP_211352662.1 DUF2244 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-82)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12328.04 Da        Isoelectric Point: 9.7852

>T127506 WP_139985020.1 NZ_CP041046:c4115816-4115493 [Luteibacter pinisoli]
MTFVETPLFTRRVRDLLDDDQYTRLQHHLTLHPDAGDLIEGTGGLRKVRVAMASRGKSGGARVIYYYFGQHARVGMLLIY
AKNERDDLTSEQRATLRKIVEQWNQPP

Download         Length: 324 bp

>T127506 NZ_CP041046:c4115816-4115493 [Luteibacter pinisoli]
ATGACTTTCGTCGAGACCCCGCTGTTCACGCGGCGGGTGCGGGATCTCCTCGATGACGATCAGTACACCCGGCTTCAACA
CCACCTCACGCTTCACCCCGACGCAGGCGACCTCATCGAAGGCACCGGTGGCCTCCGCAAGGTTCGTGTCGCCATGGCGA
GTCGGGGAAAGAGCGGTGGCGCGCGCGTCATCTACTATTACTTTGGACAGCATGCTCGCGTTGGCATGCTTCTGATTTAC
GCGAAGAACGAGCGGGACGACCTGACGTCCGAACAACGTGCGACTTTGCGAAAAATCGTCGAACAATGGAATCAACCGCC
ATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10691.12 Da        Isoelectric Point: 7.0154

>AT127506 WP_139985019.1 NZ_CP041046:c4115496-4115209 [Luteibacter pinisoli]
MTTFFDELLESVQQMDEIHRGKRAPSREFQVDPTTIKAIRESTGLSQPNFAKVLDVDVGTLRNWEQGRREPTGPARALLR
AIRNDPQNVMAALVG

Download         Length: 288 bp

>AT127506 NZ_CP041046:c4115496-4115209 [Luteibacter pinisoli]
ATGACCACTTTTTTCGATGAACTGCTCGAAAGCGTCCAGCAGATGGACGAAATCCACCGTGGAAAGCGCGCGCCATCGCG
CGAGTTCCAGGTCGACCCGACCACCATCAAGGCTATCCGCGAATCCACCGGGCTATCCCAGCCAAATTTCGCCAAGGTGC
TCGATGTGGACGTGGGAACGCTCCGTAACTGGGAGCAGGGACGGCGCGAGCCCACCGGGCCGGCGAGGGCCCTGCTGCGC
GCTATCCGCAACGATCCGCAGAACGTGATGGCCGCCCTGGTGGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References