Detailed information of TA system TA127498

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 951953..952133
• Replicon: chromosome
• Accession: NZ_CP041037
• Organism: Staphylococcus aureus strain NP66

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: FIV54_RS05045
• Protein ID: WP_001801861.1
• Coordinates: 952038..952133 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	951953..952010 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FIV54_RS05015	948304..949422	+	1119	WP_000072558.1	restriction endonuclease subunit S	-
FIV54_RS05020	950070..950513	+	444	WP_000742594.1	DUF1433 domain-containing protein	-
FIV54_RS05025	950723..951070	+	348	WP_001566695.1	DUF1433 domain-containing protein	-
FIV54_RS05030	951092..951466	+	375	WP_145326054.1	DUF1433 domain-containing protein	-
FIV54_RS05035	951654..951836	+	183	Protein_921	transposase	-
FIV54_RS05040	951814..951915	-	102	WP_001791232.1	hypothetical protein	-
-	951953..952010	+	58	-	-	Antitoxin
FIV54_RS05045	952038..952133	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
FIV54_RS05055	952584..953030	+	447	WP_000747802.1	DUF1433 domain-containing protein	-
FIV54_RS05060	953715..954098	+	384	WP_000070811.1	hypothetical protein	-
FIV54_RS05065	954109..954285	+	177	WP_000375476.1	hypothetical protein	-
FIV54_RS05075	954656..955213	+	558	WP_000864138.1	ImmA/IrrE family metallo-endopeptidase	-
FIV54_RS05080	955411..955983	-	573	WP_000414212.1	hypothetical protein	-
FIV54_RS05085	956084..956425	-	342	WP_000627548.1	DUF3969 family protein	-
FIV54_RS05090	956466..957092	-	627	WP_000669019.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	933265..958858	25593

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T127498 WP_001801861.1 NZ_CP041037:c952133-952038 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T127498 NZ_CP041037:c952133-952038 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT127498 NZ_CP041037:951953-952010 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin