Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 646871..647133 Replicon chromosome
Accession NZ_CP041037
Organism Staphylococcus aureus strain NP66

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FIV54_RS03255 Protein ID WP_001802298.1
Coordinates 646871..646975 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 646970..647133 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIV54_RS03230 643668..644450 + 783 WP_000908175.1 ABC transporter ATP-binding protein -
FIV54_RS03235 644518..645375 + 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
FIV54_RS03245 646033..646191 - 159 WP_001792784.1 hypothetical protein -
FIV54_RS03255 646871..646975 + 105 WP_001802298.1 hypothetical protein Toxin
- 646970..647133 - 164 - - Antitoxin
FIV54_RS03260 647417..648508 - 1092 WP_000495682.1 hypothetical protein -
FIV54_RS03265 648774..649754 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
FIV54_RS03270 649756..650076 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FIV54_RS03275 650228..650893 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T127488 WP_001802298.1 NZ_CP041037:646871-646975 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T127488 NZ_CP041037:646871-646975 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT127488 NZ_CP041037:c647133-646970 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References