Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) fst-RNAII/-
Location 2763931..2764125 Replicon chromosome
Accession NZ_CP041012
Organism Enterococcus faecalis strain FDAARGOS_611

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag FIU23_RS14525 Protein ID WP_015543884.1
Coordinates 2763931..2764026 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 2764061..2764125 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIU23_RS14045 2759108..2760223 + 1116 WP_002364956.1 FAD-binding oxidoreductase -
FIU23_RS14050 2760292..2761446 - 1155 WP_002355280.1 mannitol-1-phosphate 5-dehydrogenase -
FIU23_RS14055 2761461..2761898 - 438 WP_002355279.1 PTS sugar transporter subunit IIA -
FIU23_RS14060 2761913..2763685 - 1773 WP_002391520.1 PTS mannitol transporter subunit IICBA -
FIU23_RS14525 2763931..2764026 + 96 WP_015543884.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2764061..2764125 - 65 NuclAT_8 - Antitoxin
FIU23_RS14070 2764296..2764730 - 435 WP_002358391.1 PTS sugar transporter subunit IIA -
FIU23_RS14075 2764741..2766774 - 2034 WP_002355275.1 transcription antiterminator -
FIU23_RS14080 2766765..2768507 - 1743 WP_002391519.1 PTS transporter subunit EIIC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(4-45)


Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3659.47 Da        Isoelectric Point: 4.6275

>T127419 WP_015543884.1 NZ_CP041012:2763931-2764026 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

>T127419 NZ_CP041012:2763931-2764026 [Enterococcus faecalis]
ATGTACGAGATTGTCACAAAAATTCTTGTGCCGATTTTTGTCGGGATTGTCCTGAAACTTGTAACCATTTGGTTGGAAAA
ACAGAACGAGGAATAA

Antitoxin


Download         Length: 65 bp

>AT127419 NZ_CP041012:c2764125-2764061 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References