Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 405996..406332 Replicon chromosome
Accession NZ_CP041012
Organism Enterococcus faecalis strain FDAARGOS_611

Toxin (Protein)


Gene name txpA Uniprot ID A0A125WAU0
Locus tag FIU23_RS02175 Protein ID WP_002391551.1
Coordinates 405996..406139 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 406283..406332 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIU23_RS02150 401712..402344 - 633 WP_002358972.1 RloB family protein -
FIU23_RS02155 402353..403648 - 1296 WP_002371641.1 AAA family ATPase -
FIU23_RS02170 404110..405726 + 1617 WP_002365430.1 phosphatase PAP2/LCP family protein -
FIU23_RS02175 405996..406139 + 144 WP_002391551.1 putative holin-like toxin Toxin
- 406071..406333 - 263 NuclAT_6 - -
- 406283..406332 + 50 NuclAT_7 - Antitoxin
FIU23_RS02180 406334..411025 - 4692 WP_002399468.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5175.17 Da        Isoelectric Point: 8.6389

>T127417 WP_002391551.1 NZ_CP041012:405996-406139 [Enterococcus faecalis]
MNVSTKIYEKRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

>T127417 NZ_CP041012:405996-406139 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAAGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTTAAAGAAGACAATAAAAAATAA

Antitoxin


Download         Length: 50 bp

>AT127417 NZ_CP041012:406283-406332 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A125WAU0

Antitoxin

Download structure file

References