Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1919183..1919462 Replicon chromosome
Accession NZ_CP041010
Organism Staphylococcus aureus strain FDAARGOS_766

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FIU19_RS10355 Protein ID WP_001802298.1
Coordinates 1919358..1919462 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1919183..1919362 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FIU19_RS10335 1915448..1916113 - 666 WP_001024094.1 SDR family oxidoreductase -
FIU19_RS10340 1916265..1916585 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FIU19_RS10345 1916587..1917567 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
FIU19_RS10350 1917833..1918924 + 1092 WP_000495671.1 lytic regulatory protein -
- 1919183..1919362 + 180 - - Antitoxin
FIU19_RS10355 1919358..1919462 - 105 WP_001802298.1 hypothetical protein Toxin
FIU19_RS10360 1919623..1920106 - 484 Protein_1899 recombinase family protein -
FIU19_RS10365 1920149..1921285 - 1137 WP_000115564.1 SAP domain-containing protein -
FIU19_RS10370 1921574..1921666 + 93 WP_001790138.1 hypothetical protein -
FIU19_RS10375 1922371..1923228 - 858 WP_033841791.1 Cof-type HAD-IIB family hydrolase -
FIU19_RS10380 1923296..1924078 - 783 WP_000908177.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T127401 WP_001802298.1 NZ_CP041010:c1919462-1919358 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T127401 NZ_CP041010:c1919462-1919358 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 180 bp

>AT127401 NZ_CP041010:1919183-1919362 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References