Detailed information of TA system TA127351

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2623774..2623956
• Replicon: chromosome
• Accession: NZ_CP040998
• Organism: Staphylococcus aureus strain FDAARGOS_773

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: FIU14_RS13350
• Protein ID: WP_001801861.1
• Coordinates: 2623861..2623956 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2623774..2623833 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FIU14_RS13335	2622912..2623289	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
FIU14_RS13340	2623483..2623659	+	177	Protein_2524	transposase	-
FIU14_RS13345	2623637..2623738	-	102	WP_001791893.1	hypothetical protein	-
-	2623774..2623833	+	60	-	-	Antitoxin
FIU14_RS13350	2623861..2623956	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
FIU14_RS13360	2624159..2624302	+	144	WP_001549059.1	transposase	-
FIU14_RS13370	2624906..2625289	+	384	WP_000070812.1	hypothetical protein	-
FIU14_RS13375	2625300..2625476	+	177	WP_000375476.1	hypothetical protein	-
FIU14_RS13380	2625478..2625663	+	186	WP_000809857.1	hypothetical protein	-
FIU14_RS13385	2625777..2626418	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
FIU14_RS13390	2626636..2627187	-	552	WP_000414205.1	hypothetical protein	-
FIU14_RS13395	2627285..2627629	-	345	WP_000627551.1	DUF3969 family protein	-
FIU14_RS13400	2627670..2628296	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2603859..2661397	57538

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T127351 WP_001801861.1 NZ_CP040998:c2623956-2623861 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T127351 NZ_CP040998:c2623956-2623861 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT127351 NZ_CP040998:2623774-2623833 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin