Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 4491107..4491329 Replicon chromosome
Accession NZ_CP040667
Organism Escherichia coli strain S17-1

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag FGH86_RS21950 Protein ID WP_000141634.1
Coordinates 4491222..4491329 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 4491107..4491173 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGH86_RS21925 4486548..4487450 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
FGH86_RS21930 4487461..4488444 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
FGH86_RS21935 4488441..4489445 + 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
FGH86_RS21940 4489475..4490746 - 1272 WP_001295225.1 transporter -
- 4491107..4491173 - 67 - - Antitoxin
FGH86_RS21950 4491222..4491329 + 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
FGH86_RS21955 4491416..4493095 - 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
FGH86_RS21960 4493092..4493283 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
FGH86_RS21965 4493280..4494851 - 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
FGH86_RS21970 4495124..4495312 + 189 WP_001063318.1 YhjR family protein -
FGH86_RS21975 4495324..4496076 + 753 Protein_4248 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T126465 WP_000141634.1 NZ_CP040667:4491222-4491329 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T126465 NZ_CP040667:4491222-4491329 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT126465 NZ_CP040667:c4491173-4491107 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References