Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2220387..2220603 Replicon chromosome
Accession NZ_CP040665
Organism Staphylococcus aureus strain D592

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FFX42_RS11290 Protein ID WP_001802298.1
Coordinates 2220499..2220603 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2220387..2220442 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFX42_RS11270 2216593..2217258 - 666 WP_001024095.1 SDR family oxidoreductase -
FFX42_RS11275 2217410..2217730 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FFX42_RS11280 2217732..2218709 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
FFX42_RS11285 2218975..2220066 + 1092 WP_000495669.1 hypothetical protein -
- 2220387..2220442 + 56 - - Antitoxin
FFX42_RS11290 2220499..2220603 - 105 WP_001802298.1 hypothetical protein Toxin
FFX42_RS11300 2221283..2221441 + 159 WP_001792784.1 hypothetical protein -
FFX42_RS11310 2222099..2222956 - 858 WP_000370927.1 Cof-type HAD-IIB family hydrolase -
FFX42_RS11315 2223024..2223806 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T126431 WP_001802298.1 NZ_CP040665:c2220603-2220499 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T126431 NZ_CP040665:c2220603-2220499 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT126431 NZ_CP040665:2220387-2220442 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References