Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1894460..1894640 Replicon chromosome
Accession NZ_CP040665
Organism Staphylococcus aureus strain D592

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag FFX42_RS09295 Protein ID WP_001801861.1
Coordinates 1894460..1894555 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1894583..1894640 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFX42_RS09265 1889623..1890273 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
FFX42_RS09270 1890354..1891349 + 996 WP_000070642.1 DUF4352 domain-containing protein -
FFX42_RS09275 1891424..1892050 + 627 WP_000669024.1 hypothetical protein -
FFX42_RS09280 1892091..1892432 + 342 WP_000627540.1 DUF3969 family protein -
FFX42_RS09285 1892533..1893105 + 573 WP_000414216.1 hypothetical protein -
FFX42_RS09290 1893303..1894315 - 1013 Protein_1785 IS3 family transposase -
FFX42_RS09295 1894460..1894555 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1894583..1894640 - 58 - - Antitoxin
FFX42_RS09300 1894678..1894779 + 102 WP_001792025.1 hypothetical protein -
FFX42_RS09305 1894757..1894918 - 162 Protein_1788 transposase -
FFX42_RS09310 1894909..1895403 - 495 Protein_1789 transposase -
FFX42_RS09315 1895855..1897084 - 1230 WP_000072627.1 restriction endonuclease subunit S -
FFX42_RS09320 1897077..1898633 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
FFX42_RS09325 1898797..1898931 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA / selk 1870442..1921473 51031


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T126423 WP_001801861.1 NZ_CP040665:1894460-1894555 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T126423 NZ_CP040665:1894460-1894555 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT126423 NZ_CP040665:c1894640-1894583 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References