126413

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3661196..3661418 Replicon chromosome
Accession NZ_CP040664
Organism Escherichia coli strain KR2009

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag FE384_RS17875 Protein ID WP_000141634.1
Coordinates 3661196..3661303 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3661352..3661418 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE384_RS17850 3656449..3657201 - 753 Protein_3475 cellulose biosynthesis protein BcsQ -
FE384_RS17855 3657213..3657401 - 189 WP_001063318.1 YhjR family protein -
FE384_RS17860 3657674..3659245 + 1572 WP_138817882.1 cellulose biosynthesis protein BcsE -
FE384_RS17865 3659242..3659433 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
FE384_RS17870 3659430..3661109 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
FE384_RS17875 3661196..3661303 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3661352..3661418 + 67 - - Antitoxin
FE384_RS17885 3661779..3663050 + 1272 WP_001295225.1 transporter -
FE384_RS17890 3663080..3664084 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
FE384_RS17895 3664081..3665064 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
FE384_RS17900 3665075..3665977 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T126413 WP_000141634.1 NZ_CP040664:c3661303-3661196 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T126413 NZ_CP040664:c3661303-3661196 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT126413 NZ_CP040664:3661352-3661418 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References