Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3663518..3663740 Replicon chromosome
Accession NZ_CP040663
Organism Escherichia coli strain EK2009

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag FE383_RS17885 Protein ID WP_000141634.1
Coordinates 3663518..3663625 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3663674..3663740 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE383_RS17860 3658771..3659523 - 753 Protein_3479 cellulose biosynthesis protein BcsQ -
FE383_RS17865 3659535..3659723 - 189 WP_001063318.1 YhjR family protein -
FE383_RS17870 3659996..3661567 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
FE383_RS17875 3661564..3661755 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
FE383_RS17880 3661752..3663431 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
FE383_RS17885 3663518..3663625 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3663674..3663740 + 67 - - Antitoxin
FE383_RS17895 3664101..3665372 + 1272 WP_001295225.1 transporter -
FE383_RS17900 3665402..3666406 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
FE383_RS17905 3666403..3667386 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
FE383_RS17910 3667397..3668299 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T126370 WP_000141634.1 NZ_CP040663:c3663625-3663518 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T126370 NZ_CP040663:c3663625-3663518 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT126370 NZ_CP040663:3663674-3663740 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References