Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3832868..3833090 Replicon chromosome
Accession NZ_CP040643
Organism Escherichia coli strain BE104

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag FGC38_RS18860 Protein ID WP_000141634.1
Coordinates 3832868..3832975 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3833024..3833090 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGC38_RS18835 3828121..3828873 - 753 Protein_3662 cellulose biosynthesis protein BcsQ -
FGC38_RS18840 3828885..3829073 - 189 WP_001063318.1 YhjR family protein -
FGC38_RS18845 3829346..3830917 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
FGC38_RS18850 3830914..3831105 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
FGC38_RS18855 3831102..3832781 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
FGC38_RS18860 3832868..3832975 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3833024..3833090 + 67 - - Antitoxin
FGC38_RS18870 3833451..3834722 + 1272 WP_001295225.1 transporter -
FGC38_RS18875 3834752..3835756 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
FGC38_RS18880 3835753..3836736 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
FGC38_RS18885 3836747..3837649 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T126283 WP_000141634.1 NZ_CP040643:c3832975-3832868 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T126283 NZ_CP040643:c3832975-3832868 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT126283 NZ_CP040643:3833024-3833090 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References