Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-YefM |
Location | 239759..240274 | Replicon | chromosome |
Accession | NZ_CP040635 | ||
Organism | Acidipropionibacterium jensenii strain FAM 19038 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | A0A3S4V1K2 |
Locus tag | FEZ32_RS01115 | Protein ID | WP_028702688.1 |
Coordinates | 239759..240013 (-) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | A0A3S4UWW3 |
Locus tag | FEZ32_RS01120 | Protein ID | WP_028702687.1 |
Coordinates | 240014..240274 (-) | Length | 87 a.a. |
Genomic Context
Location: 242112..243014 (903 bp)
Type: Others
Protein ID: WP_138679706.1
Type: Others
Protein ID: WP_138679706.1
Location: 234810..235337 (528 bp)
Type: Others
Protein ID: WP_175415686.1
Type: Others
Protein ID: WP_175415686.1
Location: 235334..235711 (378 bp)
Type: Others
Protein ID: WP_051238192.1
Type: Others
Protein ID: WP_051238192.1
Location: 235798..236397 (600 bp)
Type: Others
Protein ID: WP_138679701.1
Type: Others
Protein ID: WP_138679701.1
Location: 236414..238309 (1896 bp)
Type: Others
Protein ID: WP_138679702.1
Type: Others
Protein ID: WP_138679702.1
Location: 238338..238703 (366 bp)
Type: Others
Protein ID: WP_154655309.1
Type: Others
Protein ID: WP_154655309.1
Location: 238970..239509 (540 bp)
Type: Others
Protein ID: WP_138679704.1
Type: Others
Protein ID: WP_138679704.1
Location: 239759..240013 (255 bp)
Type: Toxin
Protein ID: WP_028702688.1
Type: Toxin
Protein ID: WP_028702688.1
Location: 240014..240274 (261 bp)
Type: Antitoxin
Protein ID: WP_028702687.1
Type: Antitoxin
Protein ID: WP_028702687.1
Location: 240564..240884 (321 bp)
Type: Others
Protein ID: WP_028702686.1
Type: Others
Protein ID: WP_028702686.1
Location: 240977..242050 (1074 bp)
Type: Others
Protein ID: WP_138679705.1
Type: Others
Protein ID: WP_138679705.1
Location: 243015..244334 (1320 bp)
Type: Others
Protein ID: WP_138679707.1
Type: Others
Protein ID: WP_138679707.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FEZ32_RS13420 | 234810..235337 | - | 528 | WP_175415686.1 | methylated-DNA--[protein]-cysteine S-methyltransferase | - |
FEZ32_RS13425 | 235334..235711 | - | 378 | WP_051238192.1 | DUF1801 domain-containing protein | - |
FEZ32_RS01095 | 235798..236397 | - | 600 | WP_138679701.1 | histone deacetylase | - |
FEZ32_RS01100 | 236414..238309 | - | 1896 | WP_138679702.1 | ABC transporter ATP-binding protein/permease | - |
FEZ32_RS01105 | 238338..238703 | - | 366 | WP_154655309.1 | hypothetical protein | - |
FEZ32_RS01110 | 238970..239509 | - | 540 | WP_138679704.1 | GNAT family N-acetyltransferase | - |
FEZ32_RS01115 | 239759..240013 | - | 255 | WP_028702688.1 | Txe/YoeB family addiction module toxin | Toxin |
FEZ32_RS01120 | 240014..240274 | - | 261 | WP_028702687.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
FEZ32_RS01125 | 240564..240884 | - | 321 | WP_028702686.1 | HigA family addiction module antidote protein | - |
FEZ32_RS01130 | 240977..242050 | - | 1074 | WP_138679705.1 | redox-regulated ATPase YchF | - |
FEZ32_RS01135 | 242112..243014 | + | 903 | WP_138679706.1 | VOC family protein | - |
FEZ32_RS01140 | 243015..244334 | - | 1320 | WP_138679707.1 | M18 family aminopeptidase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 9970.31 Da Isoelectric Point: 7.2747
>T126232 WP_028702688.1 NZ_CP040635:c240013-239759 [Acidipropionibacterium jensenii]
VRLVWDPSAWEDYTHWQTIDRRVLKRVNTLIDSCLREPFAGIGKPEQLKYGAQGAWSRRITDEHRLVYLVDGDDLVILQA
RYHY
VRLVWDPSAWEDYTHWQTIDRRVLKRVNTLIDSCLREPFAGIGKPEQLKYGAQGAWSRRITDEHRLVYLVDGDDLVILQA
RYHY
Download Length: 255 bp
>T126232 NZ_CP040635:c240013-239759 [Acidipropionibacterium jensenii]
GTGCGGCTGGTCTGGGACCCGTCTGCATGGGAGGACTACACGCACTGGCAGACCATCGATCGTCGCGTGCTGAAGCGAGT
CAACACGCTCATCGACTCCTGCCTTCGTGAGCCGTTCGCGGGTATCGGGAAACCGGAGCAGTTGAAGTATGGCGCGCAGG
GGGCATGGTCGCGCCGTATCACCGATGAGCACCGGCTGGTGTATCTCGTCGACGGGGACGACCTCGTGATCCTCCAGGCC
CGCTACCACTACTGA
GTGCGGCTGGTCTGGGACCCGTCTGCATGGGAGGACTACACGCACTGGCAGACCATCGATCGTCGCGTGCTGAAGCGAGT
CAACACGCTCATCGACTCCTGCCTTCGTGAGCCGTTCGCGGGTATCGGGAAACCGGAGCAGTTGAAGTATGGCGCGCAGG
GGGCATGGTCGCGCCGTATCACCGATGAGCACCGGCTGGTGTATCTCGTCGACGGGGACGACCTCGTGATCCTCCAGGCC
CGCTACCACTACTGA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9780.93 Da Isoelectric Point: 4.8839
>AT126232 WP_028702687.1 NZ_CP040635:c240274-240014 [Acidipropionibacterium jensenii]
MSISASEARRTLFPLIERINEDREAIEIVSRKGNAVLMPADEYTAWQETAYLFRSPANARRLLDAYERARAGKVETHALD
RADEDA
MSISASEARRTLFPLIERINEDREAIEIVSRKGNAVLMPADEYTAWQETAYLFRSPANARRLLDAYERARAGKVETHALD
RADEDA
Download Length: 261 bp
>AT126232 NZ_CP040635:c240274-240014 [Acidipropionibacterium jensenii]
ATGTCTATCAGTGCCAGCGAGGCGCGCAGGACGCTGTTCCCGCTCATCGAGCGCATCAATGAAGACCGCGAGGCCATCGA
GATCGTCTCCCGCAAGGGCAACGCAGTGTTGATGCCCGCCGACGAGTACACGGCCTGGCAGGAGACGGCCTATCTGTTCC
GCTCACCTGCGAATGCTCGGCGACTGCTCGATGCCTACGAGCGTGCCCGCGCTGGGAAGGTCGAGACGCACGCCCTCGAC
CGTGCGGACGAGGATGCTTGA
ATGTCTATCAGTGCCAGCGAGGCGCGCAGGACGCTGTTCCCGCTCATCGAGCGCATCAATGAAGACCGCGAGGCCATCGA
GATCGTCTCCCGCAAGGGCAACGCAGTGTTGATGCCCGCCGACGAGTACACGGCCTGGCAGGAGACGGCCTATCTGTTCC
GCTCACCTGCGAATGCTCGGCGACTGCTCGATGCCTACGAGCGTGCCCGCGCTGGGAAGGTCGAGACGCACGCCCTCGAC
CGTGCGGACGAGGATGCTTGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3S4V1K2 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3S4UWW3 |