Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 239759..240274 Replicon chromosome
Accession NZ_CP040635
Organism Acidipropionibacterium jensenii strain FAM 19038

Toxin (Protein)


Gene name yoeB Uniprot ID A0A3S4V1K2
Locus tag FEZ32_RS01115 Protein ID WP_028702688.1
Coordinates 239759..240013 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A3S4UWW3
Locus tag FEZ32_RS01120 Protein ID WP_028702687.1
Coordinates 240014..240274 (-) Length 87 a.a.

Genomic Context


FEZ32_RS01135FEZ32_RS13420FEZ32_RS13425FEZ32_RS01095FEZ32_RS01100FEZ32_RS01105FEZ32_RS01110FEZ32_RS01115FEZ32_RS01120FEZ32_RS01125FEZ32_RS01130FEZ32_RS01140
Location: 242112..243014 (903 bp)
Type: Others
Protein ID: WP_138679706.1
Location: 234810..235337 (528 bp)
Type: Others
Protein ID: WP_175415686.1
Location: 235334..235711 (378 bp)
Type: Others
Protein ID: WP_051238192.1
Location: 235798..236397 (600 bp)
Type: Others
Protein ID: WP_138679701.1
Location: 236414..238309 (1896 bp)
Type: Others
Protein ID: WP_138679702.1
Location: 238338..238703 (366 bp)
Type: Others
Protein ID: WP_154655309.1
Location: 238970..239509 (540 bp)
Type: Others
Protein ID: WP_138679704.1
Location: 239759..240013 (255 bp)
Type: Toxin
Protein ID: WP_028702688.1
Location: 240014..240274 (261 bp)
Type: Antitoxin
Protein ID: WP_028702687.1
Location: 240564..240884 (321 bp)
Type: Others
Protein ID: WP_028702686.1
Location: 240977..242050 (1074 bp)
Type: Others
Protein ID: WP_138679705.1
Location: 243015..244334 (1320 bp)
Type: Others
Protein ID: WP_138679707.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FEZ32_RS13420234810..235337-528WP_175415686.1methylated-DNA--[protein]-cysteine S-methyltransferase-
FEZ32_RS13425235334..235711-378WP_051238192.1DUF1801 domain-containing protein-
FEZ32_RS01095235798..236397-600WP_138679701.1histone deacetylase-
FEZ32_RS01100236414..238309-1896WP_138679702.1ABC transporter ATP-binding protein/permease-
FEZ32_RS01105238338..238703-366WP_154655309.1hypothetical protein-
FEZ32_RS01110238970..239509-540WP_138679704.1GNAT family N-acetyltransferase-
FEZ32_RS01115239759..240013-255WP_028702688.1Txe/YoeB family addiction module toxinToxin
FEZ32_RS01120240014..240274-261WP_028702687.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
FEZ32_RS01125240564..240884-321WP_028702686.1HigA family addiction module antidote protein-
FEZ32_RS01130240977..242050-1074WP_138679705.1redox-regulated ATPase YchF-
FEZ32_RS01135242112..243014+903WP_138679706.1VOC family protein-
FEZ32_RS01140243015..244334-1320WP_138679707.1M18 family aminopeptidase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-84)

Antitoxin

(2-70)


Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 9970.31 Da        Isoelectric Point: 7.2747

>T126232 WP_028702688.1 NZ_CP040635:c240013-239759 [Acidipropionibacterium jensenii]
VRLVWDPSAWEDYTHWQTIDRRVLKRVNTLIDSCLREPFAGIGKPEQLKYGAQGAWSRRITDEHRLVYLVDGDDLVILQA
RYHY

Download         Length: 255 bp

>T126232 NZ_CP040635:c240013-239759 [Acidipropionibacterium jensenii]
GTGCGGCTGGTCTGGGACCCGTCTGCATGGGAGGACTACACGCACTGGCAGACCATCGATCGTCGCGTGCTGAAGCGAGT
CAACACGCTCATCGACTCCTGCCTTCGTGAGCCGTTCGCGGGTATCGGGAAACCGGAGCAGTTGAAGTATGGCGCGCAGG
GGGCATGGTCGCGCCGTATCACCGATGAGCACCGGCTGGTGTATCTCGTCGACGGGGACGACCTCGTGATCCTCCAGGCC
CGCTACCACTACTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9780.93 Da        Isoelectric Point: 4.8839

>AT126232 WP_028702687.1 NZ_CP040635:c240274-240014 [Acidipropionibacterium jensenii]
MSISASEARRTLFPLIERINEDREAIEIVSRKGNAVLMPADEYTAWQETAYLFRSPANARRLLDAYERARAGKVETHALD
RADEDA

Download         Length: 261 bp

>AT126232 NZ_CP040635:c240274-240014 [Acidipropionibacterium jensenii]
ATGTCTATCAGTGCCAGCGAGGCGCGCAGGACGCTGTTCCCGCTCATCGAGCGCATCAATGAAGACCGCGAGGCCATCGA
GATCGTCTCCCGCAAGGGCAACGCAGTGTTGATGCCCGCCGACGAGTACACGGCCTGGCAGGAGACGGCCTATCTGTTCC
GCTCACCTGCGAATGCTCGGCGACTGCTCGATGCCTACGAGCGTGCCCGCGCTGGGAAGGTCGAGACGCACGCCCTCGAC
CGTGCGGACGAGGATGCTTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A3S4V1K2


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A3S4UWW3

References