Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 1995072..1995682 | Replicon | chromosome |
Accession | NZ_CP040634 | ||
Organism | Acidipropionibacterium acidipropionici strain FAM 19036 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | FEZ30_RS09295 | Protein ID | WP_138573710.1 |
Coordinates | 1995072..1995353 (+) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | graA | Uniprot ID | - |
Locus tag | FEZ30_RS09300 | Protein ID | WP_138573712.1 |
Coordinates | 1995377..1995682 (+) | Length | 102 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FEZ30_RS09275 | 1990366..1991499 | - | 1134 | WP_062820489.1 | glycosyltransferase | - |
FEZ30_RS09280 | 1991504..1991938 | - | 435 | WP_062820488.1 | RDD family protein | - |
FEZ30_RS09285 | 1991962..1993251 | - | 1290 | WP_126132979.1 | hypothetical protein | - |
FEZ30_RS09290 | 1993464..1994885 | + | 1422 | WP_138573708.1 | type I glutamate--ammonia ligase | - |
FEZ30_RS09295 | 1995072..1995353 | + | 282 | WP_138573710.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
FEZ30_RS09300 | 1995377..1995682 | + | 306 | WP_138573712.1 | HigA family addiction module antidote protein | Antitoxin |
FEZ30_RS09305 | 1996147..1997163 | - | 1017 | WP_138573714.1 | YdcF family protein | - |
FEZ30_RS09310 | 1997288..1998106 | + | 819 | WP_138573716.1 | Nif3-like dinuclear metal center hexameric protein | - |
FEZ30_RS09315 | 1998114..1999406 | + | 1293 | WP_138573718.1 | threonine/serine exporter family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10770.16 Da Isoelectric Point: 9.9572
>T126228 WP_138573710.1 NZ_CP040634:1995072-1995353 [Acidipropionibacterium acidipropionici]
VIRSFKNTDTKKVWNREYVRAFGPELQRAAQKKLRLLNAASELNSLRVPPGNRLEKLVGGRDGQHSIRINDQYRICFVWT
DNGADDVEITDYH
VIRSFKNTDTKKVWNREYVRAFGPELQRAAQKKLRLLNAASELNSLRVPPGNRLEKLVGGRDGQHSIRINDQYRICFVWT
DNGADDVEITDYH
Download Length: 282 bp
>T126228 NZ_CP040634:1995072-1995353 [Acidipropionibacterium acidipropionici]
GTGATCCGGTCCTTCAAGAACACCGACACGAAGAAGGTCTGGAACCGCGAATATGTCCGCGCATTCGGACCCGAGCTGCA
ACGCGCCGCGCAGAAGAAGCTTCGCCTCCTCAACGCGGCCTCAGAACTGAACAGCCTTCGGGTGCCGCCGGGAAATCGCT
TGGAGAAGCTGGTCGGCGGCCGCGACGGCCAGCACTCCATCCGCATCAACGACCAGTACCGAATCTGCTTCGTGTGGACC
GACAACGGAGCAGACGACGTCGAGATCACCGACTATCACTGA
GTGATCCGGTCCTTCAAGAACACCGACACGAAGAAGGTCTGGAACCGCGAATATGTCCGCGCATTCGGACCCGAGCTGCA
ACGCGCCGCGCAGAAGAAGCTTCGCCTCCTCAACGCGGCCTCAGAACTGAACAGCCTTCGGGTGCCGCCGGGAAATCGCT
TGGAGAAGCTGGTCGGCGGCCGCGACGGCCAGCACTCCATCCGCATCAACGACCAGTACCGAATCTGCTTCGTGTGGACC
GACAACGGAGCAGACGACGTCGAGATCACCGACTATCACTGA
Antitoxin
Download Length: 102 a.a. Molecular weight: 11170.71 Da Isoelectric Point: 4.8182
>AT126228 WP_138573712.1 NZ_CP040634:1995377-1995682 [Acidipropionibacterium acidipropionici]
MATASKAHDPITPGEILLTEFLEPMGITQYRLAQATGLSQTRISEIVRGKRAITTDTALRLSKALGVDDRFWINIQTDYD
LEVERDLHGDELAKVTTLVAS
MATASKAHDPITPGEILLTEFLEPMGITQYRLAQATGLSQTRISEIVRGKRAITTDTALRLSKALGVDDRFWINIQTDYD
LEVERDLHGDELAKVTTLVAS
Download Length: 306 bp
>AT126228 NZ_CP040634:1995377-1995682 [Acidipropionibacterium acidipropionici]
ATGGCGACAGCATCGAAGGCACACGACCCGATCACTCCCGGTGAGATCCTGCTGACTGAGTTTCTTGAGCCGATGGGCAT
CACGCAGTACCGCCTCGCCCAGGCCACTGGACTCTCCCAGACCCGGATCAGCGAGATCGTGCGCGGCAAGCGCGCCATCA
CCACCGATACCGCCCTCCGGCTGTCCAAGGCCCTCGGGGTCGACGACCGCTTCTGGATCAACATCCAGACCGACTACGAC
CTCGAGGTCGAGCGCGACCTGCACGGCGACGAACTGGCCAAGGTGACCACCCTGGTCGCGAGCTGA
ATGGCGACAGCATCGAAGGCACACGACCCGATCACTCCCGGTGAGATCCTGCTGACTGAGTTTCTTGAGCCGATGGGCAT
CACGCAGTACCGCCTCGCCCAGGCCACTGGACTCTCCCAGACCCGGATCAGCGAGATCGTGCGCGGCAAGCGCGCCATCA
CCACCGATACCGCCCTCCGGCTGTCCAAGGCCCTCGGGGTCGACGACCGCTTCTGGATCAACATCCAGACCGACTACGAC
CTCGAGGTCGAGCGCGACCTGCACGGCGACGAACTGGCCAAGGTGACCACCCTGGTCGCGAGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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