126223

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2601328..2601512 Replicon chromosome
Accession NZ_CP040625
Organism Staphylococcus aureus strain JKD6004-DR

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag FF960_RS13435 Protein ID WP_000482650.1
Coordinates 2601405..2601512 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2601328..2601388 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FF960_RS13420 2596858..2597025 - 168 WP_001790576.1 hypothetical protein -
FF960_RS13425 2597256..2598989 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
FF960_RS13430 2599014..2600777 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2601328..2601388 + 61 - - Antitoxin
FF960_RS13435 2601405..2601512 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
FF960_RS13440 2601645..2602031 - 387 WP_000779358.1 flippase GtxA -
FF960_RS13445 2602299..2603441 + 1143 WP_001176863.1 glycerate kinase -
FF960_RS13450 2603501..2604160 + 660 WP_000831298.1 membrane protein -
FF960_RS13455 2604342..2605553 + 1212 WP_138663906.1 multidrug effflux MFS transporter -
FF960_RS13460 2605676..2606149 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T126223 WP_000482650.1 NZ_CP040625:c2601512-2601405 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T126223 NZ_CP040625:c2601512-2601405 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT126223 NZ_CP040625:2601328-2601388 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References