126220

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2309584..2309847 Replicon chromosome
Accession NZ_CP040625
Organism Staphylococcus aureus strain JKD6004-DR

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FF960_RS11900 Protein ID WP_001802298.1
Coordinates 2309743..2309847 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2309584..2309748 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FF960_RS11880 2305767..2306432 - 666 WP_001024094.1 SDR family oxidoreductase -
FF960_RS11885 2306584..2306904 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FF960_RS11890 2306906..2307886 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
FF960_RS11895 2308152..2309243 + 1092 WP_000495671.1 lytic regulatory protein -
- 2309584..2309748 + 165 - - Antitoxin
FF960_RS11900 2309743..2309847 - 105 WP_001802298.1 hypothetical protein Toxin
FF960_RS11905 2310008..2310491 - 484 Protein_2243 recombinase family protein -
FF960_RS11910 2310534..2311670 - 1137 WP_000115564.1 SAP domain-containing protein -
FF960_RS11915 2311959..2312051 + 93 WP_001790138.1 hypothetical protein -
FF960_RS11920 2312756..2313613 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
FF960_RS11925 2313681..2314463 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T126220 WP_001802298.1 NZ_CP040625:c2309847-2309743 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T126220 NZ_CP040625:c2309847-2309743 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT126220 NZ_CP040625:2309584-2309748 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References