Detailed information of TA system TA126209

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1929732..1929914
• Replicon: chromosome
• Accession: NZ_CP040625
• Organism: Staphylococcus aureus strain JKD6004-DR

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: FF960_RS09530
• Protein ID: WP_001801861.1
• Coordinates: 1929732..1929827 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1929855..1929914 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FF960_RS09480	1925392..1926018	+	627	WP_000669046.1	hypothetical protein	-
FF960_RS09485	1926059..1926403	+	345	WP_000627551.1	DUF3969 family protein	-
FF960_RS09490	1926501..1927052	+	552	WP_000414205.1	hypothetical protein	-
FF960_RS09495	1927270..1927911	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
FF960_RS09500	1928025..1928210	-	186	WP_000809857.1	hypothetical protein	-
FF960_RS09505	1928212..1928388	-	177	WP_000375476.1	hypothetical protein	-
FF960_RS09510	1928399..1928782	-	384	WP_000070811.1	hypothetical protein	-
FF960_RS09520	1929386..1929529	-	144	WP_001549059.1	transposase	-
FF960_RS09530	1929732..1929827	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1929855..1929914	-	60	-	-	Antitoxin
FF960_RS09535	1929950..1930051	+	102	WP_001791893.1	hypothetical protein	-
FF960_RS09540	1930029..1930205	-	177	Protein_1830	transposase	-
FF960_RS09545	1930399..1930776	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1922832..1948433	25601

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T126209 WP_001801861.1 NZ_CP040625:1929732-1929827 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T126209 NZ_CP040625:1929732-1929827 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT126209 NZ_CP040625:c1929914-1929855 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin