Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2553791..2553975 Replicon chromosome
Accession NZ_CP040619
Organism Staphylococcus aureus strain J01

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag FF957_RS13260 Protein ID WP_000482650.1
Coordinates 2553868..2553975 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2553791..2553851 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FF957_RS13245 2549321..2549488 - 168 WP_001789936.1 hypothetical protein -
FF957_RS13250 2549719..2551452 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
FF957_RS13255 2551477..2553240 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2553791..2553851 + 61 - - Antitoxin
FF957_RS13260 2553868..2553975 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
FF957_RS13265 2554109..2554495 - 387 WP_000779358.1 flippase GtxA -
FF957_RS13270 2554763..2555905 + 1143 WP_001176863.1 glycerate kinase -
FF957_RS13275 2555965..2556624 + 660 WP_000831298.1 membrane protein -
FF957_RS13280 2556806..2558017 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
FF957_RS13285 2558140..2558613 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T126168 WP_000482650.1 NZ_CP040619:c2553975-2553868 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T126168 NZ_CP040619:c2553975-2553868 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT126168 NZ_CP040619:2553791-2553851 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References