Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2263595..2263812 Replicon chromosome
Accession NZ_CP040619
Organism Staphylococcus aureus strain J01

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FF957_RS11730 Protein ID WP_001802298.1
Coordinates 2263708..2263812 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2263595..2263650 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FF957_RS11710 2259789..2260454 - 666 WP_001024094.1 SDR family oxidoreductase -
FF957_RS11715 2260606..2260926 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FF957_RS11720 2260928..2261908 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
FF957_RS11725 2262174..2263265 + 1092 WP_000495671.1 lytic regulatory protein -
- 2263595..2263650 + 56 - - Antitoxin
FF957_RS11730 2263708..2263812 - 105 WP_001802298.1 hypothetical protein Toxin
FF957_RS11735 2263973..2264456 - 484 Protein_2212 recombinase family protein -
FF957_RS11740 2264499..2265635 - 1137 WP_000115564.1 SAP domain-containing protein -
FF957_RS11745 2265924..2266016 + 93 WP_001790138.1 hypothetical protein -
FF957_RS11750 2266721..2267578 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
FF957_RS11755 2267646..2268428 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T126166 WP_001802298.1 NZ_CP040619:c2263812-2263708 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T126166 NZ_CP040619:c2263812-2263708 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT126166 NZ_CP040619:2263595-2263650 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References