Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2212637..2212854 Replicon chromosome
Accession NZ_CP040560
Organism Staphylococcus aureus strain Col52-A5

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FA001_RS11345 Protein ID WP_001802298.1
Coordinates 2212750..2212854 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2212637..2212692 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FA001_RS11325 2208774..2209439 - 666 WP_001024094.1 SDR family oxidoreductase -
FA001_RS11330 2209591..2209911 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FA001_RS11335 2209913..2210893 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
FA001_RS11340 2211159..2212250 + 1092 WP_000495671.1 lytic regulatory protein -
- 2212637..2212692 + 56 - - Antitoxin
FA001_RS11345 2212750..2212854 - 105 WP_001802298.1 hypothetical protein Toxin
FA001_RS11350 2213015..2213498 - 484 Protein_2138 recombinase family protein -
FA001_RS11355 2213541..2214677 - 1137 WP_000115564.1 SAP domain-containing protein -
FA001_RS11360 2214966..2215058 + 93 WP_001790138.1 hypothetical protein -
FA001_RS11365 2215763..2216620 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
FA001_RS11370 2216688..2217470 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T126024 WP_001802298.1 NZ_CP040560:c2212854-2212750 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T126024 NZ_CP040560:c2212854-2212750 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT126024 NZ_CP040560:2212637-2212692 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References