Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2110860..2111044 Replicon chromosome
Accession NZ_CP040233
Organism Staphylococcus aureus strain GD1696

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag FD747_RS10545 Protein ID WP_000482647.1
Coordinates 2110937..2111044 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2110860..2110920 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FD747_RS10530 2106314..2106481 - 168 WP_001798790.1 hypothetical protein -
FD747_RS10535 2106712..2108445 - 1734 WP_138765706.1 ABC transporter ATP-binding protein/permease -
FD747_RS10540 2108470..2110233 - 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
- 2110860..2110920 + 61 - - Antitoxin
FD747_RS10545 2110937..2111044 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
FD747_RS10550 2111178..2111564 - 387 WP_000779355.1 flippase GtxA -
FD747_RS10555 2111831..2112973 + 1143 WP_001176859.1 glycerate kinase -
FD747_RS10560 2113033..2113692 + 660 WP_000831300.1 hypothetical protein -
FD747_RS10565 2113880..2115091 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
FD747_RS10570 2115214..2115687 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T125143 WP_000482647.1 NZ_CP040233:c2111044-2110937 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T125143 NZ_CP040233:c2111044-2110937 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT125143 NZ_CP040233:2110860-2110920 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References