Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2567712..2567896 Replicon chromosome
Accession NZ_CP040232
Organism Staphylococcus aureus strain GD1706

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag FD746_RS13070 Protein ID WP_000482647.1
Coordinates 2567789..2567896 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2567712..2567772 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FD746_RS13055 2563166..2563333 - 168 WP_001798790.1 hypothetical protein -
FD746_RS13060 2563564..2565297 - 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
FD746_RS13065 2565322..2567085 - 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
- 2567712..2567772 + 61 - - Antitoxin
FD746_RS13070 2567789..2567896 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
FD746_RS13075 2568030..2568416 - 387 WP_000779355.1 flippase GtxA -
FD746_RS13080 2568683..2569825 + 1143 WP_149888548.1 glycerate kinase -
FD746_RS13085 2569885..2570544 + 660 WP_000831300.1 hypothetical protein -
FD746_RS13090 2570732..2571943 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
FD746_RS13095 2572066..2572539 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T125134 WP_000482647.1 NZ_CP040232:c2567896-2567789 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T125134 NZ_CP040232:c2567896-2567789 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT125134 NZ_CP040232:2567712-2567772 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References