125111

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2318692..2318876 Replicon chromosome
Accession NZ_CP040230
Organism Staphylococcus aureus strain GD1108

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag FD491_RS11215 Protein ID WP_000482647.1
Coordinates 2318692..2318799 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2318816..2318876 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FD491_RS11190 2314049..2314522 + 474 WP_000456489.1 GyrI-like domain-containing protein -
FD491_RS11195 2314645..2315856 - 1212 WP_001191974.1 multidrug effflux MFS transporter -
FD491_RS11200 2316044..2316703 - 660 WP_000831300.1 hypothetical protein -
FD491_RS11205 2316763..2317905 - 1143 WP_001176859.1 glycerate kinase -
FD491_RS11210 2318172..2318558 + 387 WP_000779355.1 flippase GtxA -
FD491_RS11215 2318692..2318799 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2318816..2318876 - 61 - - Antitoxin
FD491_RS11220 2319503..2321266 + 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
FD491_RS11225 2321291..2323024 + 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
FD491_RS11230 2323255..2323422 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T125111 WP_000482647.1 NZ_CP040230:2318692-2318799 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T125111 NZ_CP040230:2318692-2318799 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT125111 NZ_CP040230:c2318876-2318816 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References