125103

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2450376..2450560 Replicon chromosome
Accession NZ_CP040229
Organism Staphylococcus aureus strain GD487

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag FD482_RS12165 Protein ID WP_000482647.1
Coordinates 2450453..2450560 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2450376..2450436 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FD482_RS12150 2445830..2445997 - 168 WP_001798790.1 hypothetical protein -
FD482_RS12155 2446228..2447961 - 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
FD482_RS12160 2447986..2449749 - 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
- 2450376..2450436 + 61 - - Antitoxin
FD482_RS12165 2450453..2450560 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
FD482_RS12170 2450694..2451080 - 387 WP_000779355.1 flippase GtxA -
FD482_RS12175 2451347..2452489 + 1143 WP_001176859.1 glycerate kinase -
FD482_RS12180 2452549..2453208 + 660 WP_000831300.1 hypothetical protein -
FD482_RS12185 2453396..2454607 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
FD482_RS12190 2454730..2455203 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T125103 WP_000482647.1 NZ_CP040229:c2450560-2450453 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T125103 NZ_CP040229:c2450560-2450453 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT125103 NZ_CP040229:2450376-2450436 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References