125101

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2138324..2138587 Replicon chromosome
Accession NZ_CP040229
Organism Staphylococcus aureus strain GD487

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FD482_RS10535 Protein ID WP_001802298.1
Coordinates 2138483..2138587 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2138324..2138488 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FD482_RS10515 2134509..2135174 - 666 WP_001024099.1 SDR family oxidoreductase -
FD482_RS10520 2135326..2135646 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FD482_RS10525 2135648..2136628 + 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
FD482_RS10530 2136894..2137985 + 1092 WP_000495673.1 hypothetical protein -
- 2138324..2138488 + 165 - - Antitoxin
FD482_RS10535 2138483..2138587 - 105 WP_001802298.1 hypothetical protein Toxin
FD482_RS10540 2139267..2139425 + 159 WP_001792784.1 hypothetical protein -
FD482_RS10545 2139861..2139953 + 93 WP_000220902.1 hypothetical protein -
FD482_RS10550 2140083..2140940 - 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
FD482_RS10555 2141008..2141790 - 783 WP_000908191.1 ABC transporter ATP-binding protein -
FD482_RS10560 2142080..2142688 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T125101 WP_001802298.1 NZ_CP040229:c2138587-2138483 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T125101 NZ_CP040229:c2138587-2138483 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT125101 NZ_CP040229:2138324-2138488 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References