Detailed information of TA system TA124943

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): prlF-yhaV (relBE)/YhaV-PrlF
• Location: 550961..551799
• Replicon: plasmid unnamed1
• Accession: NZ_CP040096
• Organism: Pantoea sp. SO10

Toxin (Protein)

• Gene name: yhaV
• Uniprot ID: -
• Locus tag: FCN45_RS22060
• Protein ID: WP_210421288.1
• Coordinates: 551317..551799 (+)
• Length: 161 a.a.

Antitoxin (Protein)

• Gene name: prlF
• Uniprot ID: -
• Locus tag: FCN45_RS22055
• Protein ID: WP_101761693.1
• Coordinates: 550961..551299 (+)
• Length: 113 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FCN45_RS22025	546075..547142	+	1068	WP_137387278.1	SDR family oxidoreductase	-
FCN45_RS22030	547310..547579	-	270	WP_101761698.1	DUF1471 domain-containing protein	-
FCN45_RS22035	547742..548371	-	630	WP_110866775.1	DUF1109 family protein	-
FCN45_RS22040	548358..548915	-	558	WP_137387279.1	sigma-70 family RNA polymerase sigma factor	-
FCN45_RS22045	548933..550162	-	1230	WP_137387280.1	thioredoxin family protein	-
FCN45_RS22050	550178..550744	-	567	WP_110866778.1	peroxiredoxin	-
FCN45_RS22055	550961..551299	+	339	WP_101761693.1	type II toxin-antitoxin system PrlF family antitoxin	Antitoxin
FCN45_RS22060	551317..551799	+	483	WP_210421288.1	type II toxin-antitoxin system YhaV family toxin	Toxin
FCN45_RS22065	551961..552626	-	666	WP_137387281.1	TetR/AcrR family transcriptional regulator	-
FCN45_RS22070	552706..554226	+	1521	WP_137387282.1	MFS transporter	-
FCN45_RS22075	554232..555647	-	1416	WP_137387283.1	amidohydrolase family protein	-
FCN45_RS22080	555655..556623	-	969	WP_137387284.1	ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	hcp/tssD	1..744154	744154

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin endonuclease, YhaV (12-147)

Antitoxin

• PrlF antitoxin (14-112)

Sequences

Toxin

Protein

• Length: 161 a.a.
• Molecular weight: 18763.41 Da
• Isoelectric Point: 9.6795

>T124943 WP_210421288.1 NZ_CP040096:551317-551799 [Pantoea sp. SO10]
VDYMEINGWKFYFHACFTAQVTSLAQEVLQLKVEKPHEYHKKKQTKLLAAIYKVVTEVIARDPLNSQFRQGGTLGDENRY
WYRAKFLQQFRLFFRCSEQSKTIILGWVNDFGTLRAYESKNDAYKTFKRMLDAGHPPSDWGQLLRESTGESGFLFRAPFS

Nucleotide

• Length: 483 bp

>T124943 NZ_CP040096:551317-551799 [Pantoea sp. SO10]
GTGGACTACATGGAAATCAACGGATGGAAATTTTATTTCCACGCTTGTTTTACTGCTCAGGTAACGTCTTTAGCGCAGGA
AGTGTTGCAGCTTAAAGTTGAAAAACCGCATGAATACCATAAAAAGAAACAGACGAAATTACTGGCAGCAATTTATAAGG
TCGTTACAGAAGTTATTGCGCGAGATCCGCTGAATTCCCAGTTTCGACAAGGGGGAACTTTGGGGGATGAAAATCGATAT
TGGTATCGCGCGAAATTTTTGCAGCAGTTTCGATTGTTTTTCCGCTGTAGCGAACAGAGTAAAACCATCATTCTTGGCTG
GGTGAATGATTTTGGCACATTACGCGCTTACGAAAGTAAGAACGATGCATACAAAACATTTAAGAGGATGTTGGATGCCG
GACATCCACCGAGTGATTGGGGACAGCTACTGCGTGAATCGACAGGCGAATCGGGTTTTCTTTTCCGGGCACCATTCTCA
TAA

Antitoxin

Protein

• Length: 113 a.a.
• Molecular weight: 12499.09 Da
• Isoelectric Point: 4.1760

>AT124943 WP_101761693.1 NZ_CP040096:550961-551299 [Pantoea sp. SO10]
VFKFDLVDVSLRAESRLTERSQTTIPAAIRDALQLKPGEIIEYSLLSGGKVIISKQNDEQDDPAVLHFLTFLERDMVNNP
QHIHSVPVEFWSGLENLVAGIDVDLDAPLTDD

Nucleotide

• Length: 339 bp

>AT124943 NZ_CP040096:550961-551299 [Pantoea sp. SO10]
GTGTTTAAATTTGATCTAGTGGATGTATCACTCCGTGCAGAGTCGAGGCTGACAGAACGGAGTCAAACAACTATTCCAGC
GGCAATTCGCGATGCTCTACAGCTTAAACCGGGTGAAATTATCGAATATTCCCTGTTATCGGGCGGTAAAGTCATCATTT
CTAAGCAAAATGATGAGCAGGATGATCCCGCTGTACTGCATTTTCTGACTTTTCTCGAACGAGATATGGTGAATAACCCG
CAGCATATTCACTCAGTTCCTGTCGAATTTTGGTCAGGTCTGGAAAATTTGGTCGCTGGAATTGATGTTGATTTAGATGC
TCCGCTCACGGATGACTAA